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Table 6 ORs (95%CI) of the susceptibility genotypes of the combination of the ALDH2 and MTHFR genes related to lesions of esophagus a

From: Multi-susceptibility genes associated with the risk of the development stages of esophageal squamous cell cancer in Feicheng County

  Crude OR(95%CI) Adjusted OR(95%CI)
ALDH2 MTHFR BCH ESCD ESCC BCH ESCD ESCC
2*2/1*2 TC/TT 4.00
(2.28-7.17)
3.92
(2.06-8.11)
9.31
(3.81-23.12)
4.03
(2.14-7.57)
3.70
(1.74-7.87)
8.72
(3.24-23.48)
2*2/1*2 CC 3.95 (2.16-7.42) 4.44
(2.25-9.60)
4.02
(1.58-10.94)
4.21
(2.14-8.29)
4.68
(2.11-10.38)
4.45
(1.54-12.87)
1*1 TC/TT 1.37
(0.65-2.50)
1.43
(0.67-3.29)
1.87
(0.68-5.45)
1.18
(0.56-2.49)
1.23
(0.51-2.95)
1.80
(0.57-5.68)
1*1 CC 1.00 1.00 1.00 1.00 1.00 1.00
  1. a: Adjusted for age, sex, income, school year, smoking, drinking and family history of esophageal cancer. Abbreviations: BCH, basal cell hyperplasia; ESCD, esophageal squamous cell dysplasia; ESCC, Esophageal Squamous cell cancer.