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Table 6 ORs (95%CI) of the susceptibility genotypes of the combination of the ALDH2 and MTHFR genes related to lesions of esophagus a

From: Multi-susceptibility genes associated with the risk of the development stages of esophageal squamous cell cancer in Feicheng County

 

Crude OR(95%CI)

Adjusted OR(95%CI)

ALDH2

MTHFR

BCH

ESCD

ESCC

BCH

ESCD

ESCC

2*2/1*2

TC/TT

4.00

(2.28-7.17)

3.92

(2.06-8.11)

9.31

(3.81-23.12)

4.03

(2.14-7.57)

3.70

(1.74-7.87)

8.72

(3.24-23.48)

2*2/1*2

CC

3.95 (2.16-7.42)

4.44

(2.25-9.60)

4.02

(1.58-10.94)

4.21

(2.14-8.29)

4.68

(2.11-10.38)

4.45

(1.54-12.87)

1*1

TC/TT

1.37

(0.65-2.50)

1.43

(0.67-3.29)

1.87

(0.68-5.45)

1.18

(0.56-2.49)

1.23

(0.51-2.95)

1.80

(0.57-5.68)

1*1

CC

1.00

1.00

1.00

1.00

1.00

1.00

  1. a: Adjusted for age, sex, income, school year, smoking, drinking and family history of esophageal cancer. Abbreviations: BCH, basal cell hyperplasia; ESCD, esophageal squamous cell dysplasia; ESCC, Esophageal Squamous cell cancer.