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Table 2 Distribution of selected variables in the BCH, ESCD, ESCC and controls

From: Multi-susceptibility genes associated with the risk of the development stages of esophageal squamous cell cancer in Feicheng County

Feature BCH
(n = 270)
ESCD
(n = 262)
ESCC
(n = 226)
Controls
(n = 246)
x 2 (P c )
Gender (n,%)      
   Male 185(68.5) 151 (57.7) 162 (71.7) 125(50.8) 29.062
   Female 85(31.5) 111 (42.3) 64 (28.3) 121(49.2) (<0.001)
Age(yr) (n,%)     
   <50 70(26.0) 40(15.3) 38(16.8) 142(57.7) 150.471
   50- 138(51.1) 138(52.7) 102(45.1) 66(26.8) (<0.001)
   ≥60 62(23.0) 84(32.1) 86(38.1) 38(15.4)  
School (yr) (n,%)     
   ≤6 110 (40.9) 148 (56.5) 144 (63.7) 102(41.5) 39.792
   9 129(47.7) 92 (35.1) 72(31.9) 120(48.8) (<0.001)
   ≥10 31(11.5) 22 (8.4) 10(4.4) 24(9.8)  
Income per year ($) (n,%)     
   <150 129(47.7) 134 (51.1) 98 (43.4) 164(66.7) 36.494
   150- 117(43.4) 92(35.1) 94(41.6) 66(26.8) (<0.001)
   ≥350 24(8.9) 36(13.7) 34(15.0) 16(6.5)  
Smoking indexa(n,%)     
   None 109 (40.4) 148 (56.9) 80 (35.4) 148(60.2) 60.087
   <450 63 (23.4) 38(14.6) 36 (15.9) 48(19.5) (<0.001)
   ≥450 98 (36.2) 74(28.5) 110 (48.7) 50(20.3)  
Alcohol drinking Statusb(n,%)     
   None 114 (42.4) 136 (53.1) 76 (33.6) 138(56.1) 68.712
   <100 43(16.0) 44(17.2) 32 (14.2) 62(25.2) (<0.001)
   ≥100 112(41.6) 76(29.7) 118 (52.2) 46(18.7)  
Family history of esophagus cancer (n,%)    
   None 231 (85.5) 2021(77.1) 190(84.1) 222(90.2) 17.027
   yes 39 (14.5) 60(22.9) 36(15.9) 24(9.8) (<0.001)
  1. a smoking index = cigarette/day × number of smoking years.b alcohol drinking ≥100g/day means heavy drinker. c P : Chi-square test was for proportions among the four groups.
  2. Abbreviations: BCH, Basal cell hyperplasia; ESCD, esophageal squamous cell dysplasia; ESCC, Esophageal Squamous cell cancer.