Table 4 Comparison of three studies.
| Â | Roulet et al.[16] | Kim et al.[17] | This study | |||
|---|---|---|---|---|---|---|
| Â | All subjects | Controls | All subjects | Controls | All subjects | Controls |
Number of subjects | 429 (196 males) | 370 (167 males) | 73 | 69 (35 males) | 416 (250 males) | 165 (77 males) |
Age | 45.1 ± 16.7 | 43.3 ± 16.5 | ND | 38.9 ± 11.9 | 47.4 ± 13.6 | 45.1 ± 14.4 |
BMI | 25.6 ± 4.2 | 24.9 ± 3.8 | ND | 22.6 ± 2.5 | 22.1 ± 3.1 | 20.2 ± 2.0 |
Population | Subjects for free medical checkups | Living doners for liver and kidney | Subjects for annual medical checkups | |||
Factors related to liver stiffness | Â | |||||
Age | NS (p = 0.06) | ND | ND | NS | NS (p = 0.11) | NS |
Gender | p = 0.0002 | p = 0.0006 | ND | NS | p = 0.02 | NS (p = 0.10) |
BMI | p = 0.0005 | ND | ND | NS | p < 0.0001 | NS |
Metabolic syndrome | p < 0.0001 | / | ND | / | ND | / |
Alcohol consumption | ND | ND | ND | Details not described | x2 = 7.15, p = 0.008 | NS |
Abnormal LFT | ND | ND | ND | Details not described | p < 0.0001 | NS |
Fatty liver | ND | ND | ND | Details not described | p < 0.0001 | NS |
Criteria to define healthy | Â | |||||
MS excluded | Â | Yes | Â | Yes | Â | Yes |
HF excluded | Â | No description | Â | Yes | Â | Yes |
Normal LFT | Â | Yes | Â | Yes | Â | Yes |
Alcohol consumption (g/d) |  | ≤30 |  | No |  | ≤20 |
BMI (kg/m2) | Â | non-obese(< 30) | Â | No | Â | < 23 |
Exclusion of fatty liver | Â | No | Â | Yes by CT scan | Â | Yes by ultrasonography |
Liver stiffness (mean ± SD) | 5.81 ± 1.54 (male) 5.23 ± 1.59 (female) | 5.60 ± 1.30 (male) 5.05 ± 1.49(female) | ND | 4.5 ± 0.4 | 4.88 ± 1.77(male) 4.52 ± 1.11(female) | 4.30 ± 0.81 |
Normal upper limit of liver stiffness | Â | 8.0 (male, 90 percentile) 7.8 (female, 90 percentile) | Â | 5.3(95th percentile) | Â | 5.9 (Mean + 2SD) 5.5 (Non drinker) |