AAR


Cutoff value

Spe%

Sen%

PPV%

NPV%

F0F3 (n = 136 )

F4 (n = 21)

AUC [95% CI]


< 1

42.8

67.6

88.4

16.9

92/44

12/9

0.468[0.3770.559]

> 1

67.6

42.8

16.9

88.4

44/92

9/12

0.610[0.4830.738]

APRI

Cutoff value

Spe%

Sen%

PPV%

NPV%

F0F1 (n = 68)

F2F4 (n = 89)

AUC [95% CI]

< 0.5

97.7

19.1

86.6

61.2

13/55

2/87

0.715[0.6350.795]

> 1.5

67.6

34.8

58.4

44.2

22/46

31/58

0.876[0.7820.971]

FIB4

Cutoff value

Spe%

Sen%

PPV%

NPV%

F0F2 (n = 102)

F3F4 (n = 55 )

AUC [95% CI]

< 1.45

85.4

51

86.6

48.4

52/50

8/47

0.732 [0.6550.809]

> 3.25

82.3

59.2

64

79.2

18/84

33/22

0.545[0.4560.635]

FI

Cutoff value

Spe%

Sen%

PPV%

NPV%

F0F1 (n = 68)

F2F4 (n = 89)

AUC [95% CI]

< 2.1

58.4

100

64.7

100

68/0

37/52

0.939[0.9030.974]

Cutoff value

Spe%

Sen%

PPV%

NPV%

F0F3 (n = 136)

F4 (n = 21)

AUC [95% CI]

> 3.3

100

38.1

100

91.2

0/136

8/13

0.990[0.9791.001]

 Spearman rank correlation coefficient (Rindex) for AAR = 0.130, APRI = 0.444, FIB4 = 0.494 and FI = 0.578