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Table 2 Distribution of each variable according to fibrosis stages

From: A comparison of four fibrosis indexes in chronic HCV: Development of new fibrosis-cirrhosis index (FCI)

Factor F0 (n = 29) F1(n = 39) F2(n = 34) F3(n = 34) F4(n = 21) Pvalue
Age 25.9 ± 2.4 37.9 ± 9.5 42.8 ± 7.6 37.7 ± 8.5 48.4 ± 7.1 < 0.05
Sex (M/F) 19/10 35/4 26/8 20/14 14/7 0.247
Genotype (1a/3a) 8/21 4/35 3/31 3/31 4/17 0.258
HAI score 3.8 ± 2.1 6.05 ± 2.8 6.8 ± 3.2 6.9 ± 4.02 7.6 ± 2.9 < 0.05
Viral load 6.2 × 105 ± 1.2 × 106 1.3 ± × 107 ± 1.5 × 107 2.1 × 108 ± 2.4 × 108 2.4 × 107 ± 2.5 × 107 2.9 × 105 ± 2.9 × 105 < 0.05
Hb level 12.8 ± 1.3 12.6 ± 1.2 12.77 ± 1.7 12.9 ± 1.3 12.3 ± 1.2 0.328
Bilirubin 0.7 ± 0.1 0.88 ± 0.2 0.99 ± 0.27 1.2 ± 0.3 1.62 ± 0.31 < 0.05
ALT 120.2 ± 71.9 117.8 ± 55.3 152.1 ± 66.5 139.6 ± 56.6 147.5 ± 61.2 0.091
ALP 72.6 ± 16.8 88.1 ± 47.5 110.7 ± 45.1 208.6 ± 75.9 323.8 ± 80.1 < 0.05
AST 83.1 ± 57.9 107.1 ± 66.5 95.9 ± 51.4 106.9 ± 65.4 155.5 ± 90.6 < 0.05
Albumin 4.5 ± 0.1 4.3 ± 0.16 4.2 ± 0.18 4.08 ± 0.2 3.6 ± 0.33 < 0.05
Platelet count 191.3 ± 18.7 185.1 ± 21.2 162.1 ± 16.6 125.5 ± 18.7 81.6 ± 17.7 < 0.05
AAR 0.8 ± 0.58 1.14 ± 1.21 0.93 ± 1.1 1.02 ± 1.03 1.26 ± 0.95 0.522
APRI 1.04 ± 0.75 1.39 ± 0.87 1.40 ± 0.75 2.09 ± 1.33 4.7 ± 3.1 < 0.05
FI 1.24 ± 0.26 1.51 ± 0.28 1.81 ± 0.27 2.33 ± 0.28 3.2 ± 0.4 < 0.05
FIB-4 1.21 ± 0.95 2.17 ± 1.47 2.31 ± 1.57 3.06 ± 2.1 8.73 ± 6.59 < 0.05