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Table 2 Levels of eight hormones related to energy homeostasis, and BMI in 21 subjects, according to H. pylori eradication status

From: The effect of H. pylori eradication on meal-associated changes in plasma ghrelin and leptin

 

Median (IQR) hormone concentration (pg/ml), before and after H. pylorieradication

Comparison of values at baseline and after eradication

(p-value)

 

Baseline

Eradicated

  

Hormone

Pre-meal

Post-meal

pb

Pre-meal

Post-meal

pb

Pre-meal

Post-meal

Amylin

15

19

0.046

16

36

0.008

0.25

0.16

 

(14-43)

(15-54)

 

(15-50)

(15-106)

   

Insulin

243

584

< 0.001

265

763

< 0.001

0.39

0.28

 

(129-414)

(462-1,475)

 

(139-558)

(430-2,100)

   

Ghrelin

1,024

231

0.004

1,710

1,586

0.12

0.51

0.005

 

(7-3,461)

(7-1,329)

 

(27-4,573)

(13-3,360)

   

GIP

15

107

0.001

27

82

0.001

0.82

0.85

 

(5-29)

(29-214)

 

(9-54)

(41-282)

   

GLP-1

28

16

0.51

36

45

0.95

0.11

0.04

 

(10-56)

(9-59)

 

(12-89)

(14-91)

   

Leptin

4,260

5,690

0.02

6,605

7,400

0.02

0.001

< 0.001

 

(1,890-6,649)

(1,765-11,350)

 

(3,517-14,600)

(4,120-17,925)

   

PP

63

107

0.005

79

112

0.001

0.31

0.23

 

(18-113)

(44-204)

 

(26-153)

(45-172)

   

PYY

39

70

0.002

61

70

0.001

0.02

0.34

 

(27-82)

(48-98)

 

(34-90)

(47-137)

   
  1. a p-values < 0.05 are indicated in bold
  2. b Wilcoxon's signed rank test comparing pre-meal and post-meal values.
  3. c Paired t-test comparing BMI at baseline to after H. pylori eradication.