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Table 1 The clinical profile of 40 patients with diffuse duodenal nodular hyperplasia.

From: Diffuse duodenal nodular lymphoid hyperplasia: a large cohort of patients etiologically related to Helicobacter pyloriinfection

Group All patients H pylori
eradicated
group
H pylori
persistent
group
P value
(Eradicated vs.
Non-eradicated)
Number of patients 40 26 14  
Age (years ± 1SD) 35.6 ± 14.6 33.6 ± 11.6 37.6 ± 15.6 0.29c
Sex (Male: Female) 23:17 15:11 8:6 0.64a
Symptoms
(Number of patients)
    
   Pain 40 26 14 1.00a
   Vomiting 38 24 14 0.41a
   Weight loss 35 23 12 0.77a
   Diarrhoea 6 4 2 0.65a
   Constipation 4 1 3 0.11a
Hemoglobin (g/dl) 9.5 ± 2.2 8.9 ± 3.2 9.7 ± 1.2 0.33c
Serum albumin (g/dl) 3.2 ± 1.1 3.4 ± 1.1 2.9 ± 1.4 0.39c
Immunoglobulins
(Number of patients)
   Normal 26 18 8 0.14a
   Elevated IgG 6 4 2 0.65a
   Elevated IgM 5 4 1 0.41a
   Elevated IgA 3 0 3 0.03a
Gastroscopic findings
(number of patients)
   No abnormality 8 6 2 0.41a
   Antral gastritis 20 11 9 0.16a
   Fundic exudative gastritis 6 4 2 0.65a
   Atrophic gastritis 4 3 1 0.56a
   Ulcerative Nodular antral disease 2 2 0 0.41a
Grade of duodenal nodular disease
(Number of patients)
   Grade 1 4 2 2 0.71b
   Grade 2 10 7 3  
   Grade 3 20 14 6  
   Grade 4 6 3 3  
Mean ± 1SD Score 2.70 ± 0.84 2.69 ± 0.79 2.71 ± 0.96 0.94c
Follow up months (mean ± 1SD) 24 ± 12.5 (6-56) 22 ± 14.5 (6-54) 26 ± 12.9 (8-56) 0.65c
  1. a = Fisher's exact test 2 × 2 table; b = Fisher's exact test rxc table; c = students t test.
  2. Key: The profile of 26 patients in whom H. pylori infection was eradicated and 14 patients in whom H. pylori infection was resistant to eradication therapy are compared.