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Figure 9 | BMC Gastroenterology

Figure 9

From: Presence of intestinal Mycobacterium avium subspecies paratuberculosis(MAP) DNA is not associated with altered MMP expression in ulcerative colitis

Figure 9

Expression of MMP-28 in UC patients (n = 49). mRNA results were determined by RT-PCR. MMP-28 gene expression was not significantly different in UC patients with intestinal MAP detection and those without (p = 0.370) and did not differ between patients receiving an anti-inflammatory therapy (AIT) and those without AIT (p = 0.602). Further stratification into subgroups of patients receiving 5-amino salicylic acid (5-ASA) and its derivatives, corticosteroids or immunomodulators (azathioprine and infliximab) revealed no significant differences in MMP-28 expression between patients treated with the respective substance and those not receiving the respective agent. Note, that some patients received more than one substance class and therefore appear in more than one subgroup.

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