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Figure 2 | BMC Gastroenterology

Figure 2

From: Isoflurane Preconditioning at Clinically Relevant Doses Induce Protective Effects of Heme Oxygenase-1 on Hepatic Ischemia Reperfusion in Rats

Figure 2

Effects of isoflurane preconditioning on hepatic histology after ischemia reperfusion (IR) procedure (n = 12 in each group). (A) Hepatic tissue histological changes were processed with H&E staining for light microscopy examination. Photograph depicted typical pattern of focal necrosis (black arrows) after ischemic degeneration of hepatocytes around the central venous area. More seriously necrosis was shown in both zinc protoporphyrin (Znpp) pretreated and IR groups compared in sham group. Magnification: 200 × Scale bar = 200 μm. (B) There was no obvious necrosis in sham group. Areas of necrosis were significantly lower in isoflurane and hemin pretreated groups than in IR group (* P < 0.05 vs. IR).

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