Table 1 NARANJO ADR PROBABILITY SCALE calculated for our case summed up 9 points, indicating a very probable association between acute pericarditis and interferon treatment
From: Acute pericarditis due to pegylated interferon alpha therapy for chronic HCV hepatitis - Case report
Question | Response | Points |
|---|---|---|
Are there previous conclusion reports on this reaction? | Yes | + 1 |
Did the adverse event appear after the suspect drug was administered? | Yes | +2 |
Did the AR improve when the drug was discontinued or a specific antagonist was administered? | Yes | + 1 |
Did the AR reappear when drug was readministered? | Yes | + 2 |
Are there alternate causes [other than the drug] that could solely have caused the reaction? | No | +2 |
Did the reaction reappear when a placebo was given? | don't know | 0 |
Was the drug detected in the blood [or other fluids] in a concentration known to be toxic? | No | 0 |
Was the reaction more severe when the dose was increased, or less severe when the dose was decreased? | don't know | 0 |
Did the patient have a similar reaction to the same or similar drugs in any previous exposure? | No | 0 |
Was the adverse event confirmed by objective evidence? | Yes | + 1 |
Total | Â | 9 |