Table 4 Comparison of the Temporal Characteristics in PFC, IC and ACC among Subgroups of GERD Patients during Intraesophageal Acid and Psychological Anticipation Stimuli (Mean ± SE)

HCL

PFC

Onset t (TR)

-

60.8 ± 2.7

66.6 ± 3.2

57.4 ± 0.9

60.3 ± 1.3

2.65

0.074

Peak t (TR)

-

85.7 ± 3.0

93.7 ± 3.5

91.8 ± 1.8

93.8 ± 1.4

2.12

0.126

50%Offset t (TR)

-

109.8 ± 4.8

119.9 ± 3.5

123.6 ± 3.6

122.8 ± 3.5

2.48

0.088

MAX (%)

-

2.7 ± 0.2

1.3 ± 0.3

1.6 ± 0.3

1.7 ± 0.2

5.05

0.008

b/c

ACC

Onset t (TR)

-

63 ± 2

-

-

60 ± 3

(0.60)

0.565

Peak t (TR)

-

88.3 ± 2

-

-

91 ± 3

(0.74)

0.481

50%Offset t (TR)

-

117 ± 3

-

-

119 ± 4

(0.37)

0.722

MAX (%)

-

4.2 ± 0.5

-

-

1.6 ± 0.1

(5.09)

0.001

b/e

IC

Onset t (TR)

-

57 ± 3

56 ± 1

-

62 ± 3

0.64

0.546

Peak t (TR)

-

88 ± 2

90 ± 4

-

95 ± 4

0.82

0.464

50%Offset t (TR)

-

125 ± 2

138 ± 4

-

122 ± 6

1.02

0.391

MAX (%)

-

1.9 ± 0.1

1.7 ± 0.3

-

2.0 ± 0.3

0.34

0.720

PSY

PFC

Onset t (TR)

57 ± 2.2

56.3 ± 1.5

58.5 ± 3.0

52.3 ± 1.0

50.8 ± 0.4

4.72

0.008

e/c

Peak t (TR)

83 ± 2.6

83.3 ± 2.0

105.0 ± 7.9

99.3 ± 7.2

70.8 ± 2.4

10.88

0.000

e/c,e/d

50%Offset t (TR)

117.6 ± 4.2

101.2 ± 3.6

126.5 ± 7.1

130.0 ± 10.7

126.1 ± 9.5

1.51

0.237

MAX (%)

1.7 ± 0.1

1.9 ± 0.2

2.2 ± 0.2

3.0 ± 0.3

2.5 ± 0.3

2.59

0.068

ACC

Onset t (TR)

-

-

-

54 ± 1

52 ± 1

(0.96)

0.360

Peak t (TR)

-

-

-

85 ± 5

80 ± 3

(0.96)

0.360

50%Offset t (TR)

-

-

-

117 ± 6

126 ± 7

(0.89)

0.394

MAX (%)

-

-

-

2.7 ± 0.4

1.9 ± 0.4

(1.22)

0.250

IC

Onset t (TR)

-

54 ± 1

-

52 ± 1

52 ± 1

1.17

0.350

Peak t (TR)

-

85 ± 3

-

66 ± 2

78 ± 4

9.88

0.004

d/b

50%Offset t (TR)

-

119 ± 3

-

115 ± 3

103 ± 2

5.21

0.028

e/b

MAX (%)

-

1.9 ± 0.5

-

1.3 ± 0.1

2.0 ± 0.2

1.49

0.271