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Figure 5 | BMC Gastroenterology

Figure 5

From: Differences in cerebral response to esophageal acid stimuli and psychological anticipation in GERD subtypes - An fMRI study

Figure 5

Intragroup brain activation differences during induction of psychological anticipation among GERD subgroups and control. 5A. Average intragroup cerebral activation during induction of psychological anticipation: Control group: PFC was activated. RE group: PFC and IC were activated. NERD+ group: PFC was activated. NERD-SI+ group: PFC, IC and ACC were activated. NERD-SI- group: PFC, IC and ACC were activated. 5B. Comparing psychological anticipation with actual acid infusion, based on cerebral activation (yellow-colored) and deactivation (blue-colored) in the four GERD subgroups Control: PFC was activated in psychological anticipation when compared with actual acid infusion. RE group: ACC was deactivated. The intensity of PFC in anticipation was lower than that of actual acid infusion. NERD+ group: IC was deactivated. The intensity of PFC in anticipation was lower than that of actual acid infusion NERD-SI+ group: PFC was activated more extensively during anticipation than acid infusion. NERD-SI- group: The intensity of activation of most of the PFC area and ACC in anticipation was higher, and a small part of the PFC was lower than that of actual acid infusion.

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