Representative immune-histochemical staining of SRF expression. (A) High nuclear and cytoplasmic SRF intensity of regenerative epithelial cells (arrow), some mononuclear inflammatory cells and myofibroblasts (arrowhead) of the lamina propria in gastric ulcer tissues (Magnification × 2400). (B) Increased nuclear and cytoplasmic SRF intensity of smooth muscle cells (arrow) between the deep glands (× 1200). (C) Nuclear staining of SRF in smooth muscle cells of the muscularis mucosa (arrow) and vascular wall (arrowhead) (× 600). (D) Low SRF intensity in non-ulcer tissues (× 2400). (E) The positive control of colon ulcer tissues indicates positive nuclear staining in smooth muscle cells (arrow) and nerve (arrowhead).