Figure 4
From: HMGB1 cytoplasmic translocation in patients with acute liver failure
HMGB1 cytoplasmic translocation in hepatocytes of ALF patients caused by HBV infection. A). HE staining of liver sections (×200). a, normal adults; b, chronic viral hepatitis B patients; c, ALF patients caused by hepatitis B (panel c, × 200). B). HMGB1 immunohistochemistry. d and g: healthy controls; e and h: chronic viral hepatitis B patients, f and i: ALF patients. d, e and f × 200; g, h and i × 800). Brown: HMGB1; Blue: counterstaining of nucleus with hematoxylin; Arrow: cytoplasmic HMGB1 staining in hepatocytes. C). Percentage of hepatocytes with HMGB1 cytoplasmic translocation.*, P < 0.05 versus controls or chronic hepatitis B patients.