Effects of H. pylori on AGS cells. (A) AGS cells were treated with H. pylori at the ratio of 200:1(bacterium to cells) or 500:1 for 0, 24 or 48 hours, respectively. Suppression of HSP70 in AGS by H. pylori infection was evidenced by immunoblotting. (B) H. pylori infection significantly inhibited cell proliferation in gastric epithelial cell line in a dose- and time-dependent manner. Data are mean ± SD, *P <0.05, **P <0.01.