From: The MLH12101C>A (Q701K) variant increases the risk of gastric cancer in Chinese males
Genotypes | Cases | Controls | P a | OR (95% CI) b | P b |
---|---|---|---|---|---|
-93 G>A | Â | Â | 0.736 | Â | Â |
GG | 36 (15.3%) | 42(17.5%) | Â | 1.00 | Â |
GA | 111 (47.0%) | 114(47.5%) | Â | Â | Â |
AA | 89 (37.7%) | 84(35.0%) | Â | Â | Â |
GA+AA | 200 (84.7%) | 198(82.5%) | Â | 1.18 (0.72-1.92) | 0.510 |
A allele | 61.2% | 58.8% | 0.435 | Â | Â |
-28A>G | Â | Â | 1.000c | Â | Â |
AA | 232 (98.3%) | 236 (98.3%) | Â | 1.00 | Â |
AG | 4 (1.7%) | 4 (1.7%) | Â | 1.02 (0.25-4.14) | 0.978 |
G allele | 0.85% | 0.83% | 1.000 c | Â | Â |
649C>T (R217C) | Â | Â | 0.120 c | Â | Â |
CC | 231 (97.9%) | 239 (99.6%) | Â | 1.00 | Â |
CT | 5(2.1%) | 1 (0.4%) | Â | 5.25 (0.61-45.45) | 0.132 |
T allele | 1.1% | 0.2% | 0.121 c | Â | Â |
655A>G (I219V) | Â | Â | 0.257 | Â | Â |
AA | 229 (97.0%) | 228 (95.0%) | Â | 1.00 | Â |
AG | 7 (3.0%) | 12 (5.0%) | Â | 0.58 (0.22-1.50) | 0.262 |
G allele | 1.5% | 2.5% | 0.262 | Â | Â |
1151T>A (V384D) | Â | Â | 1.000 c | Â | Â |
TT | 232 (98.3%) | 236 (98.3%) | Â | Â | Â |
TA | 4 (1.7%) | 4 (1.7%) | Â | 1.02 (0.25-4.15) | 0.976 |
A allele | 0.85% | 0.83% | 1.000 c | Â | Â |
2101C>A (Q701K) | Â | Â | 0.120 | Â | Â |
CC | 228 (96.6%) | 237 (98.8%) | Â | 1.00 | Â |
CA | 8 (3.4%) | 3 (1.3%) | Â | 2.77 (0.73 -10.57) | 0.136 |
A allele | 1.7% | 0.6% | 0.122 | Â | Â |