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Table 3 Discrepancy against a diagnostic reference.

From: Comparison of accuracy of fibrosis degree classifications by liver biopsy and non-invasive tests in chronic hepatitis C

  Discrepancy score Significant discrepancies (%)
Population # 1a 2 3 4 1a 2 3 4
Local pathologist 0.40 ± 0.58 - - - 4.9 - - -
Expert pathologist 0.17 ± 0.38 - - - 0.0 - - -
Fibrotest 0.86 ± 0.77 0.84 ± 0.80 0.86 ± 0.93 0.92 ± 0.82 17.2 18.2 21.3 22.2
FibroMeter2G 0.30 ± 0.58 0.30 ± 0.55 0.36 ± 0.62 0.38 ± 0.61 5.6 4.6 5.7 6.0
FibroMeter3G 0.11 ± 0.33 0.14 ± 0.37 0.23 ± 0.44 0.17 ± 0.40 0.5 0.7 0.9 0.9
Fibroscan - - 0.50 ± 0.79 0.64 ± 0.74 - - 12.9 12.3
p b < 10-3 < 10-3 < 10-3 < 10-3 < 10-3 < 10-3 < 10-3 < 10-3
  1. Discrepancy score and significant discrepancies (≥ 2 FM stages) with liver biopsy results as a function of fibrosis classifications by pathologists, blood tests or Fibroscan according to the 4 populations.
  2. a The reference is consensus reading of liver biopsy
  3. b by paired Cochran or Friedman test