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Table 1 Liver function test and histologic features pre- and post-prednisone

From: Autoimmune enteropathy with a CD8+ CD7-T-cell small bowel intraepithelial lymphocytosis: case report and literature review

  Pre-prednisone Post-prednisone
  Presentation 15 months 21 months 26 months
Liver Function Tests
AST (U/L) 107 43 41 65
ALT (U/L) 95 46 97 82
ALP (U/L) 240 205 110 123
Albumin (g/dL) 2.2 1.5 2.1 3.5
Histology
Histology IEL
Intact villi
Chronic inflammation
Intact villi
Duodenum + jejunum+ illeum: lymphoplastic infiltrate
Colon + cecum + rectum:
lymphoplastic infiltrate
IEL
Subtotal villous atrophy
IEL
Subtotal villous atrophy Segmental areas normal
Immuno-phenotype not obtained Jejunum + illeum: CD3 + CD5 + CD8 + CD7 - preponderance Jejunum: Polyclonal αβTCR + CD3 + preponderance
CD8 + CD25 - CD7 - (70% of total IEL)
Jejunum: Polyclonal αβTCR + CD3 + (94% of total IEL) CD8 + CD25 - CD7 - (41% of CD3 + fraction)