Table 1 Hypercoagulability study in association with post-transplant thromboses

Platelets (×10⁹/L)

327.27 ± 88.0

264.89 ± 73.7

p < 0.001

PA (%)

101.96 ± 21.5

101.79 ± 16.4

p = 0.962

APTT (seconds)

31.24 ± 6.1

31.08 ± 4.4

p = 0.866

TT (seconds)

13.8 ± 2.2

14.22 ± 1.9

p = 0.301

Fibrinogen (mg/dL)

327.3 ± 88.7

264.89 ± 73.7

p < 0.001

AT (U/dL)

107.57 ± 18.3

99.57 ± 15.3

p = 0.013

PC chromogenic (U/dL)

61.34 ± 41.9

74.69 ± 39.8

p = 0.069

PC anticoagulant (U/dL)

94.68 ± 18.99

102.61 ± 27.5

p = 0.065

PS free antigen (U/dL)

84.0 ± 12.7

77.85 ± 14.2

p = 0.038

PS functional (U/dL)

95.4 ± 24.9

83.44 ± 22.3

p = 0.011

PS total (U/dL)

90.0 ± 9.0

93.9 ± 18.3

p = 0.716

Factor VIII (UI/dL

168.77 ± 60.8

153.95 ± 56.9

p = 0.209

ACA IgG (uFl)

5.84 ± 5.0

7.56 ± 16.49

p = 0.605

ACA IgM (uFl)

11.24 ± 18.64

9.3 ± 14.68

p = 0.539

Plasma homocysteine (μmoles/L)

13.79 ± 3.35

14.31 ± 8.7

p = 0.585

Factor V Leiden mutation (N°) (heterozygous) in recipient

1/26

6/264

p = 0.618

Prothrombin 20210A mutation (N°) (heterozygous) in recipient

0/26

13/264

p = 0.247

C677T MTHFR mutation (N°) (wild type/heterozygous/homozygous) in recipient

13/8/4

102/117/37

p = 0.402

APCR

2.86 ± 0.51

2.92 ± 0.51

p = 0.582

DONOR STUDY

Factor V Leiden mutation (N°) (heterozygous) in donor

0/26

4/196

p = 0.454

Prothrombin 20210A mutation (N°) (heterozygous) in donor

1/26

6/194

p = 0.865

C677T MTHFR mutation (N°) (wild type/heterozygous/homozygous) in donor

9/14/3

63/101/28

p = 0.915