Table 3 Effect of moderate (3-5g) and low (1-3g) amounts of gluten on serum transglutaminase 2 (TG2) antibodies and small bowel mucosal TG2-targeted autoantibody deposits in treated celiac disease patients.
No | Mean daily gluten intake | Duration of gluten | Serum TG2 antibodies* | Mucosal TG2 antibody deposits† | ||
|---|---|---|---|---|---|---|
I | II | I | II | |||
Moderate amounts of gluten daily | ||||||
1 | 5.0 | 29 | 10 | 319 | 0 | +++ |
2 | 4.9 | 84 | 9 | 13 | 0 | 0 |
3 | 4.9 | 38 | 5 | 10 | 0 | + |
4 | 4.7 | 45 | 44 | 218 | + | +++ |
5 | 4.1 | 61 | 6 | 5 | 0 | 0 |
6 | 4.0 | 91 | 21 | 263 | + | +++ |
7 | 3.6 | 91 | 6 | 47 | 0 | ++ |
8 | 3.6 | 84 | 8 | 10 | ++ | + |
9 | 3.4 | 88 | 13 | 16 | 0 | 0 |
10 | 3.3 | 86 | 18 | 229 | + | +++ |
Low amounts of gluten daily | ||||||
11 | 2.8 | 89 | 6 | 7 | 0 | ++ |
12 | 2.7 | 84 | 7 | 111 | 0 | ++ |
13 | 2.6 | 81 | 7 | 5 | 0 | 0 |
14 | 2.4 | 85 | 12 | 88 | 0 | ++ |
15 | 2.2 | 103 | 9 | 9 | 0 | 0 |
16 | 2.1 | 93 | 16 | 94 | ++ | ++ |
17 | 2.1 | 85 | 9 | 8 | 0 | 0 |
18 | 2.1 | 84 | 24 | 21 | + | + |
19 | 2.1 | 83 | 8 | 8 | 0 | 0 |
20 | 1.4 | 77 | 10 | 13 | 0 | + |
21 | 1.3 | 78 | 14 | 101 | 0 | ++ |
Altogether positive outcome‡, n (%) | 9 (43%) | 11 (52%) | ||||