No
|
Mean daily gluten intake
|
Duration of gluten
|
Serum TG2 antibodies*
|
Mucosal TG2 antibody deposits†
|
---|
| | |
I
|
II
|
I
|
II
|
---|
Moderate amounts of gluten daily
| | |
1
|
5.0
|
29
|
10
|
319
|
0
|
+++
|
2
|
4.9
|
84
|
9
|
13
|
0
|
0
|
3
|
4.9
|
38
|
5
|
10
|
0
|
+
|
4
|
4.7
|
45
|
44
|
218
|
+
|
+++
|
5
|
4.1
|
61
|
6
|
5
|
0
|
0
|
6
|
4.0
|
91
|
21
|
263
|
+
|
+++
|
7
|
3.6
|
91
|
6
|
47
|
0
|
++
|
8
|
3.6
|
84
|
8
|
10
|
++
|
+
|
9
|
3.4
|
88
|
13
|
16
|
0
|
0
|
10
|
3.3
|
86
|
18
|
229
|
+
|
+++
|
Low amounts of gluten daily
| | |
11
|
2.8
|
89
|
6
|
7
|
0
|
++
|
12
|
2.7
|
84
|
7
|
111
|
0
|
++
|
13
|
2.6
|
81
|
7
|
5
|
0
|
0
|
14
|
2.4
|
85
|
12
|
88
|
0
|
++
|
15
|
2.2
|
103
|
9
|
9
|
0
|
0
|
16
|
2.1
|
93
|
16
|
94
|
++
|
++
|
17
|
2.1
|
85
|
9
|
8
|
0
|
0
|
18
|
2.1
|
84
|
24
|
21
|
+
|
+
|
19
|
2.1
|
83
|
8
|
8
|
0
|
0
|
20
|
1.4
|
77
|
10
|
13
|
0
|
+
|
21
|
1.3
|
78
|
14
|
101
|
0
|
++
|
Altogether positive outcome‡, n (%)
|
9 (43%)
|
11 (52%)
|
- Clinically significant changes between baseline (I) and 12 weeks' follow-up examination (II) are marked in bold letters. Complete challenge lasted 12 weeks (84 ± 14 days).
- * Values of ≥20 IU considered positive
- † Graded as negative (0), weak (+), moderate (++) and strong positive (+++)
- ‡ Positive outcome reported when serum antibody levels or intensity of mucosal autoantibody deposits increased.