|
VAS-IBS score
|
Controls = 52
|
IBS = 39
|
Dysmotility = 21
|
pSS = 26
|
Statistically significant p values
|
|---|
|
Abdominal pain
| | | | | |
|
Z-score
|
0.22 (-0.41-0.60)
|
-3.43 (-4.23 - -2.77)
|
-3.34 (-4.42 - -2.31)27 (12-44) ***
|
-1.08 (-2.31 - 0.04)
|
IBS vs pSS p = 0.000
|
|
Absolute score
|
95 (85-99)
|
23 (10-37) ***
| |
73 (54-97) ***
|
pSS vs Dysm p = 0.000
|
|
Diarrhoea
| | | | | |
|
Z-score
|
0.27 (-0.11-0.55)
|
-3.91 (-5.23 - -0.53)
|
-3.23 (-4.11 - -0.55)
|
-0.75 (-1.97-0.15)
|
IBS vs pSS p = 0.012
|
|
Absolute score
|
97 (90-100)
|
35 (19-83) ***
|
49 (33-69) ***
|
82 (66-98) ***
|
pSS vs Dysm p = 0.049
|
|
Constipation
| | | | | |
|
Z-score
|
0.32 (-0.39-0.76)
|
-0.69 (-2.99-0.54)
|
-1.57 (-3.32-0.60)
|
0.03 (-2.41-0.63)
| |
|
Absolute score
|
91 (78-99)
|
72 (30-95) **
|
54 (18-95) *
|
86 (42-97) *
| |
|
Bloating, flatulence
| | | | | |
|
Z-score
|
0.28 (-0.26-0.77)
|
-2.33 (-2.84 - -1.06)
|
-2.15 (-2.67 - -1.28)
|
-0.62 (-1.61-0.31)
|
IBS vs pSS p = 0.000
|
|
Absolute score
|
86 (71-99)
|
17 (3-50) ***
|
18 (7-45) ***
|
63 (37-87) ***
|
pSS vs Dysm p = 0.002
|
|
Vomiting, nausea
| | | | | |
|
Z-score
|
0.27 (0.08-0.35)
|
-3.34 (-4.55 - -0.03)
|
-4.82 (-4.81 - -0.78)
|
0.08 (-3.14-0.20)
|
IBS vs pSS p = 0.004 IBS vs Dysm p = 0.044
|
|
Absolute score
|
98 (97-100)
|
50 (34-94) ***
|
32 (12-84) ***
|
97 (54-99) ***
|
pSS vs Dysm p = 0.001
|
|
Psychological well-being
| | | | | |
|
Z-score
|
0.51 (-0.09-0.70)
|
-2.08 (-3.29 - -0.56)
|
-1.79 (-1.79-0.46)
|
-0.76 (-2.29-0.62)
|
IBS vs pSS p = 0.018
|
|
Absolute score
|
96 (84-100)
|
45 (23-74) ***
|
51 (22-94) **
|
72 (44-98) ***
| |
|
Influence on daily life
| | | | | |
|
Z-score
|
0.53 (-0.12-0.59)
|
-3.05 (-3.43 - -2.49)
|
-3.06 (-3.06 - -2.62)
|
0.20 (-1.75-0.49)
|
IBS vs pSS p = 0.000
|
|
Absolute score
|
98 (82-100)
|
11 (3-25) ***
|
8 (3-22) ***
|
88 (42-96) ***
|
pSS vs Dysm p = 0.000
|
- All p values are calculated using the z-scores. Mann Whitney U test. Patients vs controls; * < 0.05, ** < 0.01, *** < 0.001. IBS = Irritable bowel syndrome, pSS = primary Sjögren's syndrome.
