Skip to main content

Table 5 Meta-analysis of studies comparing conventional colonoscopy to NBI system.

From: Narrow-band imaging does not improve detection of colorectal polyps when compared to conventional colonoscopy: a randomized controlled trial and meta-analysis of published studies

Study (Year) Outcome Conventional colonoscopy (N) NBI system (N) RR* WMD** (95%CI) Heterogeneity (I2) §
Adler 2009
East 2009
Inoue 2008
Kaltenbach 2008
Sabbagh 2011
Mean number of polyps 1241 1238 WMD -0.07 (-0.21 to 0.07) 68%
Adler 2009
Adler 2008
East 2009
Inoue 2008
Kaltenbach 2008
Paggi 2009
Rex 2007
Sabbagh 2011
Mean number of adenomas 1768 1749 WMD -0.08 (-0.17 to 0.01) 62%
Adler 2009
Adler 2008
Inoue 2008
Kaltenbach 2008
Sabbagh 2011
Rate of patients with al least one polyp 1336 1330 RR 0.90 (0.73 to1.11) 70%
Adler 2009
Adler 2008
East 2009
Inoue 2008
Kaltenbach 2008
Paggi 2009
Rex 2007
Sabbagh 2011
Rate of patients with at least one adenoma 1763 1749 RR 0.96 (0,88 to 1.04) 0%
Adler 2009
Adler 2008
Paggi 2009
Sabbagh 2011
Rate of patients with carcinoma 1181 1169 RR 1.20 (0.58 to 2.47) 0%
  1. *Relative Risk and 95% confidence intervals (CI) for dichotomous outcomes were calculated by the Mantel-Haenszel fixed-effects model when I2 < 50%. Relative Risk and 95% confidence intervals (CI) for dichotomous outcomes were calculated by the Mantel-Haenszel random-effects model when I2 > 50%.
  2. **Mean difference and 95% confidence intervals (CI) for continuous outcomes were calculated using the inverse variance and the fixed-effects model when I2 < 50%. Mean difference and 95% confidence intervals (CI) for continuous outcomes were calculated using the inverse variance and the random-effects model when I2 > 50%.
  3. § Low, moderate, and high levels of heterogeneity approximately correspond to I2 values of 25%, 50% and 75%, respectively [35].