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Table 3 Regional variation in the prevalence of reflux symptoms and symptom-defined gastroesophageal reflux disease (GERD).

From: A population-based survey of the epidemiology of symptom-defined gastroesophageal reflux disease: the Systematic Investigation of Gastrointestinal Diseases in China

Population Reflux symptoms at least monthly
n (%)
Reflux symptoms at least weekly
n (%)
Symptom-defined GERDa
n (%)
Shanghai (n = 3151) 338 (10.7) 143 (4.5) 84 (2.7)
Beijing (n = 3168) 287 (9.1) 120 (3.8) 69 (2.2)
Wuhan (n = 3283) 532 (16.2) 245 (7.5) 169 (5.1)
Xi'an (n = 3266) 609 (18.6) 218 (6.7) 121 (3.7)
Guangzhou (n = 3210) 271 (8.4) 103 (3.2) 53 (1.7)
Total (n = 16 078) 2037 (12.7) 829 (5.2) 496 (3.1)
  1. aDefined as mild symptoms of heartburn and/or regurgitation occurring on at least 2 days a week (Reflux Disease Questionnaire [RDQ] item frequency score ≥3 for a severity score of ≥2), or moderate-to-severe symptoms of heartburn and/or regurgitation occurring on at least 1 day a week (RDQ item frequency score ≥2 for a severity score ≥3).
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