Figure 3

Histological findings of the liver specimen. A: Liver biopsy showing intracanalicular bile plugs (black arrow) and enlarged hepatocytes with feathery degeneration, indicative of intrahepatic cholestasis. Moderate inflammatory infiltration, composed of lymphocytes, neutrophils, as well as eosinophils (inset), was presented in portal area (Hematoxylin and Eosin staining, ×400). B: Expanded portal tracts accompanied by significant hepatic fibrosis (Masson Tri-chrome staining, ×100).