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Table 2 The expression of pGSK-3βTyr216 in relation to that of cell cycle-regulatory proteins

From: Constitutive activation of glycogen synthase kinase-3β correlates with better prognosis and cyclin-dependent kinase inhibitors in human gastric cancer

  Active GSK-3β
Positive (%)
Active GSK-3β
Negative (%)
Pvalue
p16    
   Positive 99 (54) 84 (46) < 0.001*
   Negative 24 (28) 63 (72)  
p21    
   Positive 38 (26) 39 (74) < 0.001*
   Negative 23 (12) 162 (88)  
p27    
   Positive 23 (59) 38 (41) 0.001*
   Negative 30 (3) 149 (97)  
p53    
   Positive 56 (55) 45 (45) 0.013*
   Negative 69 (40) 104 (60)  
pRb    
   Positive 118 (45) 142 (55) 0.208
   Negative 6 (67) 3 (33)  
Cyclin D1    
   Positive 28 (53) 25 (47) 0.202
   Negative 90 (43) 119 (57)  
  1. pRb: phospho-retinoblastoma protein.
  2. * Considered to be statistically significant (< 0.05).