Figure 4From: Evaluation of HIV protease and nucleoside reverse transcriptase inhibitors on proliferation, necrosis, apoptosis in intestinal epithelial cells and electrolyte and water transport and epithelial barrier function in mice Intestinal transport of fluid and electrolytes (mEq/min/g) in experimental mice (n = at least 5 per group) after 7 days of treatment with either nelfinavir (NFV, 100 mg/kg), indinavir (IDV, 100 mg/kg), zidovudine (AZT, 50 mg/kg) and didanosine (DDI, 100 mg/kg) or PBS. Mice undergoing protease and reverse transcriptase inhibitors were submitted to intestinal perfusion (60 min) with ringer lactate. The results are expressed as mean Ā± SEM of at least 5 mice per group. *statistical significance (P < 0.05) compared to the PBS control group by ANOVA, Bonferroni's multiple test. A: sodium; B: chloride and C: fluid transport.Back to article page