Figure 5
From: Prostaglandin E2-induced colonic secretion in patients with and without colorectal neoplasia
Indomethacin, bumetanide, and ouabain-induced inhibition of short circuit current in human colon biopsies. Inhibition of electrogenic secretion in endoscopic mucosal biopsies from the sigmoid part of colon from C-patients and N-patients. Numbers in parenthesis are numbers of biopsy specimens and numbers of patients. Decreases in short circuit current (SCC) after inhibition with 10 μM indomethacin (C-patients: 43,24), (N-patients: 21,12); 50 μM bumetanide (C-patients: 12,7), (N-patients: 8,5) and 200 nM ouabain (C-patients: 10,7), (N-patients: 8,5). * p < 0.05.