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Table 1 Incidence and size of dysplasia

From: The role of prostaglandin E2 (PGE 2) in toll-like receptor 4 (TLR4)-mediated colitis-associated neoplasia

 

WT

TLR4-/- PBS

PGE 2high dose

PGE 2low dose

 

(n = 13)

(n = 7)

(n = 8)

(n = 6)

Incidence (%)

92.3

28.6

75

33.3

Tumors/animal

(range)

3.1 ± 1.1

(1 - 15)

0.4 ± 0.2

(0 - 2)

1.5 ± 1.2*

(0 - 3)

0.3 ± 0.5

(0 - 1)

Tumor size (mm)

(range)

3.3 ± 2.1

(1 - 8)

0.4 ± 0.8

(0.5 - 1)

1.8 ± 1.3*

(1 - 4)

0.8 ± 1.1

(2 - 2)

Percentage of mucosal surface with tumor

(range)

17.4% ± 13.8

(0 - 40)

1.4% ± 2.4

(0 - 5)

6.3% ± 4.4*

(0 - 10)

1.5% ± 0.4

(0 - 3)

  1. * P < 0.05, compared to corresponding result in PBS treated control mice.