| WT | TLR4-/- PBS | PGE 2high dose | PGE 2low dose |
---|---|---|---|---|
 | (n = 13) | (n = 7) | (n = 8) | (n = 6) |
Incidence (%) | 92.3 | 28.6 | 75 | 33.3 |
Tumors/animal (range) | 3.1 ± 1.1 (1 - 15) | 0.4 ± 0.2 (0 - 2) | 1.5 ± 1.2* (0 - 3) | 0.3 ± 0.5 (0 - 1) |
Tumor size (mm) (range) | 3.3 ± 2.1 (1 - 8) | 0.4 ± 0.8 (0.5 - 1) | 1.8 ± 1.3* (1 - 4) | 0.8 ± 1.1 (2 - 2) |
Percentage of mucosal surface with tumor (range) | 17.4% ± 13.8 (0 - 40) | 1.4% ± 2.4 (0 - 5) | 6.3% ± 4.4* (0 - 10) | 1.5% ± 0.4 (0 - 3) |