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Table 1 Incidence and size of dysplasia

From: The role of prostaglandin E2 (PGE 2) in toll-like receptor 4 (TLR4)-mediated colitis-associated neoplasia

  WT TLR4-/- PBS PGE 2high dose PGE 2low dose
  (n = 13) (n = 7) (n = 8) (n = 6)
Incidence (%) 92.3 28.6 75 33.3
Tumors/animal (range) 3.1 ± 1.1 (1 - 15) 0.4 ± 0.2 (0 - 2) 1.5 ± 1.2* (0 - 3) 0.3 ± 0.5 (0 - 1)
Tumor size (mm) (range) 3.3 ± 2.1 (1 - 8) 0.4 ± 0.8 (0.5 - 1) 1.8 ± 1.3* (1 - 4) 0.8 ± 1.1 (2 - 2)
Percentage of mucosal surface with tumor (range) 17.4% ± 13.8 (0 - 40) 1.4% ± 2.4 (0 - 5) 6.3% ± 4.4* (0 - 10) 1.5% ± 0.4 (0 - 3)
  1. * P < 0.05, compared to corresponding result in PBS treated control mice.