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Table 3 Odds ratios (95% confidence intervals) for incident diabetes, across sex specific quartile groups of Fatty Liver Index and NAFLD fatty liver at baseline; The D.E.S.I.R. Study.

From: Nine-year incident diabetes is predicted by fatty liver indices: the French D.E.S.I.R. study

MEN

 

no adjustment

with adjustment*

 

diabetics/n

OR (95% CI)

P

OR (95% CI)

P

Fatty Liver Index

< 15.52

8/466

1

 

1

 

15.52 - 33.38

23/464

2.99 [1.32 - 6.74]

0.008

1.92 [0.81 - 4.56]

0.1

33.39 - 57.67

30/465

3.95 [1.79 - 8.71]

0.0007

2.17 [0.92 - 5.11]

0.07

> 57.67

79/466

11.69 [5.58 - 24.48]

0.0001

3.89 [1.65 - 9.14]

0.002

Fatty Liver Index

≤ 57.67

61/1395

1

 

1

 

>57.67

79/466

4.46 [3.14 - 6.35]

0.0001

2.04 [1.30 - 3.20]

0.002

NAFLD fatty liver score

< -2.34

10/462

1

 

1

 

-2.34 - -1.94

22/462

2.26 [1.06 - 4.83]

0.03

1.97 [0.88 - 4.37 ]

0.1

-1.93 - -1.15

25/462

2.59 [1.23 - 5.45]

0.01

2.05 [0.94 - 4.51 ]

0.07

> -1.15

80/462

9.47 [4.84 - 18.52]

0.0001

3.98 [1.93 - 8.20]

0.0002

NAFLD fatty liver score

≤ -1.15

57/1386

1

 

1

 

> -1.15

80/462

4.88 [3.41 - 6.99]

0.0001

2.32 [1.53 - 3.50]

0.0001

WOMEN

 

no adjustment

with adjustment a

 

diabetics/n

OR (95% CI)

P

OR (95% CI)

P

Fatty Liver Index

< 3.78

1/488

1

 

1

 

3.78 - 7.64

4/487

4.03 [0.45 - 36.12]

0.2

3.51 [0.38 - 32.13]

0.3

7.65 - 21.64

9/488

9.14 [1.15 - 72.30]

0.04

4.09 [0.49 - 33.92]

0.2

> 21.64

49/487

54.40 [7.49 - 395]

0.0001

12.78 [1.59 - 102]

0.02

Fatty Liver Index

≤ 21.64

14/1463

1

 

1

 

> 21.64

49/487

11.58 [6.33 - 21.17]

0.0001

3.78 [1.79 - 7.95]

0.0005

NAFLD fatty liver score

< -2.65

2/486

1

 

1

 

-2.65 - -2.33

7/487

3.53 [0.73 - 17.07]

0.1

2.81 [0.57 - 13.92 ]

0.2

-2.32 - -1.82

4/487

2.00 [0.37 - 10.99]

0.4

1.17 [0.20 - 6.71 ]

0.9

> - 1.82

49/486

27.13 [6.56 - 112]

0.0001

6.58 [1.48 - 29.26]

0.01

NAFLD fatty liver score

≤ -1.82

13/1460

1

 

1

 

> - 1.82

49/486

12.48 [6.71 - 23.22]

0.0001

3.95 [1.93 - 8.07]

0.0002

  1. a adjusted for age, glucose, insulin, physical activity, smoker, alcohol, diabetes in family, HTA; the NAFLD-FLS is not adjusted for insulin as insulin is already included in the NAFLD-FLS index