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Table 2 Odds ratios (95% confidence intervals) for incident diabetes, with P values for trend across baseline Fatty Liver Index classes; The D.E.S.I.R. Study.

From: Nine-year incident diabetes is predicted by fatty liver indices: the French D.E.S.I.R. study

MEN

    
 

Fatty Liver Index

P- value

trend

Adjustment factors

< 20

20-69

≥ 70

 
 

n = 594

n = 990

n = 277

 

Not adjusted

1

3.10 (1.73-5.56)

10.73 (5.86-19.65)

0.0001

Age

1

2.77 (1.54-5.01)

9.33 (5.05-17.25)

0.0001

Age + glucose

1

2.39 (1.28-4.45)

6.09 (3.17-11.70)

0.0001

Age + insulin ‡

1

1.85 (1.00-3.42)

4.28 (2.15-8.50)

0.0001

Age + physical activity

1

2.76 (1.53-5.00)

9.27 (5.00-17.19)

0.0001

Age + smoking

1

2.73 (1.51-4.93)

9.02 (4.87-16.71)

0.0001

Age + alcohol

1

2.65 (1.47-4.80)

8.15 (4.36-15.23)

0.0001

Age + diabetes in family

1

2.77 (1.53-5.00)

9.27 (5.01-17.15)

0.0001

Age + hypertension (HTA)

1

2.58 (1.42-4.68)

7.96 (4.25-14.93)

0.0001

Age + alcohol, glucose, insulin, physical activity, smoking, diabetes in family, HTA

1

1.92 (1.00-3.66)

3.43 (1.61-7.28)

0.0009

Where alcohol < 30 g/day

n = 451

n = 675

n = 144

 

Age

1

3.65 (1.69-7.86)

9.49 (4.12-21.85)

0.0001

Age + alcohol, glucose, insulin, physical activity, smoking, diabetes in family, HTA

1

2.72 (1.16-6.38)

4.71 (1.68-13.16)

0.003

WOMEN

    
 

Fatty Liver Index

P - value trend

Adjustment factors

< 20

20-69

≥ 70

 
 

n = 1430

n = 445

n = 75

 

Not adjusted

1

7.88 (4.07-15.24)

39.64 (18.75-83.78)

0.0001

Age

1

7.21 (3.64-14.28)

36.72 (17.12-78.76)

0.0001

Age + glucose

1

3.79 (1.84-7.77)

13.60 (5.92-31.24)

0.0001

Age + insulin ‡

1

4.65 (2.22-9.72)

15.49 (6.17-38.85)

0.0001

Age + physical activity

1

7.08 (3.57-14.06)

36.06 (16.78-77.48)

0.0001

Age + smoking

1

7.12 (3.59-14.11)

35.70 (16.62-76.68)

0.0001

Age + alcohol

1

7.23 (3.65-14.33)

37.13 (17.28-79.78)

0.0001

Age + diabetes in family

1

6.87 (3.45-13.70)

37.87 (17.45-82.17)

0.0001

Age + hypertension (HTA)

1

6.42 (3.21-12.85)

29.24 (13.22-64.68)

0.0001

Age + alcohol, glucose, insulin, physical activity, smoking, diabetes in family, HTA

1

3.27 (1.49-7.20)

11.05 (4.09-29.81)

0.0001

Where alcohol < 20 g/day

n = 1067

n = 320

n = 52

 

Age

1

9.79 (4.02-23.85)

66.84 (25.70-173.88)

0.0001

Age + alcohol, glucose, insulin, physical activity, smoking, diabetes in family, HTA

1

4.38 (1.62-11.83)

22.77 (6.78-76.44)

0.0001