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Table 4 Multivariate analysis of factor associated with advanced fibrosis
| Factor | Presumed fibrosis1 | Confirmed fibrosis1 |
|---|---|---|
| OR (95%CI) | ||
| All subjects n = 7395 | R2 = 0.22 | R2 = 0.20 |
| Age | 1.12 (1.10-1.14) <0.0001 | 1.13 (1.09-1.16) <0.0001 |
| Male gender | 4.31 (2.62-7.08) <0.0001 | 6.36 (2.03-22.1) 0.002 |
| Waist | 1.03 (1.01-1.04) 0.0002 | 1.05 (1.02-1.07) 0.001 |
| Triglycerides1 | 1.32 (1.21-1.45) <0.0001 | 1.22 (1.07-1.39) 0.001 |
| Total cholesterol | 0.61 (0.52-0.72) 0.04 | 0.81 (0.60-1.11) 0.19 |
| Fasting glucose | 1.15 (1.05-1.26) 0.002 | 1.11 (0.94-1.32) 0.21 |
| Reported alcohol | 1.00 (0.99-1.01) | 0.99 (0.97-1.01) 0.33 |
| CDT assays 1 n = 1076 | R2 = 0.31 | R2 = 0.31 |
| CDT | 2.09 (1.42-3.05) 0.0002 | 2.11 (1.39-3.20) 0.0005 |
| CDT assays and HCV antibody 1 testing n = 500 | R2 = 0.35 | R2 = 0.36 |
| CDT | 1.82 (1.21-2.73) 0.004 | 1.78 (1.24-2.56) 0.01 |
| HCV positive | 18.0 (2.43-132.7) 0.005 | 26.8 (2.75-261.3) 0.005 |
