|
Factor
|
Presumed fibrosis1
|
Confirmed fibrosis1
|
|---|
| | |
OR (95%CI)
|
|
All subjects n = 7395
|
R2 = 0.22
|
R2 = 0.20
|
|
Age
|
1.12 (1.10-1.14) <0.0001
|
1.13 (1.09-1.16) <0.0001
|
|
Male gender
|
4.31 (2.62-7.08) <0.0001
|
6.36 (2.03-22.1) 0.002
|
|
Waist
|
1.03 (1.01-1.04) 0.0002
|
1.05 (1.02-1.07) 0.001
|
|
Triglycerides1
|
1.32 (1.21-1.45) <0.0001
|
1.22 (1.07-1.39) 0.001
|
|
Total cholesterol
|
0.61 (0.52-0.72) 0.04
|
0.81 (0.60-1.11) 0.19
|
|
Fasting glucose
|
1.15 (1.05-1.26) 0.002
|
1.11 (0.94-1.32) 0.21
|
|
Reported alcohol
|
1.00 (0.99-1.01)
|
0.99 (0.97-1.01) 0.33
|
|
CDT assays
1
n = 1076
|
R2 = 0.31
|
R2 = 0.31
|
|
CDT
|
2.09 (1.42-3.05) 0.0002
|
2.11 (1.39-3.20) 0.0005
|
|
CDT assays and HCV antibody
1
testing n = 500
|
R2 = 0.35
|
R2 = 0.36
|
|
CDT
|
1.82 (1.21-2.73) 0.004
|
1.78 (1.24-2.56) 0.01
|
|
HCV positive
|
18.0 (2.43-132.7) 0.005
|
26.8 (2.75-261.3) 0.005
|
-
1 When CDT entered the models, the impact of serum triglycerides disappeared.
