Skip to main content

Advertisement

Table 4 Multivariate analysis of factor associated with advanced fibrosis

From: Prevalence of liver fibrosis and risk factors in a general population using non-invasive biomarkers (FibroTest)

Factor Presumed fibrosis1 Confirmed fibrosis1
   OR (95%CI)
All subjects n = 7395 R2 = 0.22 R2 = 0.20
Age 1.12 (1.10-1.14) <0.0001 1.13 (1.09-1.16) <0.0001
Male gender 4.31 (2.62-7.08) <0.0001 6.36 (2.03-22.1) 0.002
Waist 1.03 (1.01-1.04) 0.0002 1.05 (1.02-1.07) 0.001
Triglycerides1 1.32 (1.21-1.45) <0.0001 1.22 (1.07-1.39) 0.001
Total cholesterol 0.61 (0.52-0.72) 0.04 0.81 (0.60-1.11) 0.19
Fasting glucose 1.15 (1.05-1.26) 0.002 1.11 (0.94-1.32) 0.21
Reported alcohol 1.00 (0.99-1.01) 0.99 (0.97-1.01) 0.33
CDT assays 1 n = 1076 R2 = 0.31 R2 = 0.31
CDT 2.09 (1.42-3.05) 0.0002 2.11 (1.39-3.20) 0.0005
CDT assays and HCV antibody 1 testing n = 500 R2 = 0.35 R2 = 0.36
CDT 1.82 (1.21-2.73) 0.004 1.78 (1.24-2.56) 0.01
HCV positive 18.0 (2.43-132.7) 0.005 26.8 (2.75-261.3) 0.005
  1. 1 When CDT entered the models, the impact of serum triglycerides disappeared.