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Table 2 Characteristics of 209 subjects with FibroTest >0.48 (presumed advanced fibrosis) in the population without a history of liver disease

From: Prevalence of liver fibrosis and risk factors in a general population using non-invasive biomarkers (FibroTest)

Characteristics All Reinvestigated     Not reinvestigated
  Presumed fibrosis Fibrosis Confirmed Fibrosis still suspected Indeterminate All reinvestigated  
Number of subjects 209 50 27 28 105 104
Prevalence of fibrosis1 209/7,463 (2.8%) 100/7,463 (1.3%) 54/7,463 (0.7%) 56/7,463 (0.8%) 100/7,463 (1.4%) 104/7,463 (1.4%)
Cause of liver disease       
Non alcoholic fatty liver disease2 98 (47%) 18 (35%) 10 (40%) 13 (46%) 41 (39%) 57 (55%)
Alcoholic liver disease3 15 (7%) 4 (8%) 1 (4%) 4 (14%) 9 (9%) 6 (6%)
Non alcoholic and alcoholic 61 (29%) 22 (42%) 11 (44%) 6 (21%) 39 (37%) 22 (21%)
Chronic hepatitis C 6 (3.5%) 4 (8%) 0 1 (4%) 5 (5%) 1 (1%)
Chronic hepatitis B 3 (1.4%) 1 (2%) 1 (4%) 0 3 (3%) 0 (0%)
Hemochromatosis 1 (0.5%) 1 (2%) 0 0 1 (1%) 0 (0%)
Auto-immune hepatitis 1 (0.5%) 0 (0%) 1 (4%) 0 1 (1%) 0 (0%)
No risk factor 25 (12%) 2 (4%) 1 (4%) 3 (11%) 7 (7%) 18 (17%)
Liver complications       
Hepatocellular carcinoma NP 0 (0%) 0 0 0 NP
Portal hypertension NP 1 (2%) 0 0 1 (1%) NP
Stage presumed fibrosis       
Few septa 128 (61%) 26 (50%) 18 (72%) 22 (79%) 66 (63%) 62 (60%)
Many septa 56 (27%) 17 (33%) 6 (24%) 5 (18%) 28 (27%) 28 (27%)
Cirrhosis 25 (12%) 9 (17%) 1 (4%) 1 (3%) 11 (10%) 14 (13%)
Mode of confirmation4       
Elastography NP 47 (90%) (>= 7.1 kPa) 27 (100%) (5kPa-7kPa) 28 (100%) (<5kPa) 102(95%) NP
Biopsy NP 3 (5%) 0 1 (4%) 4 (4%) NP
Endoscopy NP 1 (2%) 0 0 1 (1%) NP
  1. 1 Estimated prevalence assuming that the prevalence of advanced ?brosis would be the same in the population of patients not reinvestigated. 2At least one factor of the metabolic syndrome without alcohol consumption at risk 3Alcohol consumption at risk self-reported or CDT >1.6% without metabolic factor 4Possibility of several confirmations for the same subject NP = not performed