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Table 2 Characteristics of 209 subjects with FibroTest >0.48 (presumed advanced fibrosis) in the population without a history of liver disease

From: Prevalence of liver fibrosis and risk factors in a general population using non-invasive biomarkers (FibroTest)

Characteristics

All

Reinvestigated

   

Not reinvestigated

 

Presumed fibrosis

Fibrosis Confirmed

Fibrosis still suspected

Indeterminate

All reinvestigated

 

Number of subjects

209

50

27

28

105

104

Prevalence of fibrosis1

209/7,463 (2.8%)

100/7,463 (1.3%)

54/7,463 (0.7%)

56/7,463 (0.8%)

100/7,463 (1.4%)

104/7,463 (1.4%)

Cause of liver disease

      

Non alcoholic fatty liver disease2

98 (47%)

18 (35%)

10 (40%)

13 (46%)

41 (39%)

57 (55%)

Alcoholic liver disease3

15 (7%)

4 (8%)

1 (4%)

4 (14%)

9 (9%)

6 (6%)

Non alcoholic and alcoholic

61 (29%)

22 (42%)

11 (44%)

6 (21%)

39 (37%)

22 (21%)

Chronic hepatitis C

6 (3.5%)

4 (8%)

0

1 (4%)

5 (5%)

1 (1%)

Chronic hepatitis B

3 (1.4%)

1 (2%)

1 (4%)

0

3 (3%)

0 (0%)

Hemochromatosis

1 (0.5%)

1 (2%)

0

0

1 (1%)

0 (0%)

Auto-immune hepatitis

1 (0.5%)

0 (0%)

1 (4%)

0

1 (1%)

0 (0%)

No risk factor

25 (12%)

2 (4%)

1 (4%)

3 (11%)

7 (7%)

18 (17%)

Liver complications

      

Hepatocellular carcinoma

NP

0 (0%)

0

0

0

NP

Portal hypertension

NP

1 (2%)

0

0

1 (1%)

NP

Stage presumed fibrosis

      

Few septa

128 (61%)

26 (50%)

18 (72%)

22 (79%)

66 (63%)

62 (60%)

Many septa

56 (27%)

17 (33%)

6 (24%)

5 (18%)

28 (27%)

28 (27%)

Cirrhosis

25 (12%)

9 (17%)

1 (4%)

1 (3%)

11 (10%)

14 (13%)

Mode of confirmation4

      

Elastography

NP

47 (90%) (>= 7.1 kPa)

27 (100%) (5kPa-7kPa)

28 (100%) (<5kPa)

102(95%)

NP

Biopsy

NP

3 (5%)

0

1 (4%)

4 (4%)

NP

Endoscopy

NP

1 (2%)

0

0

1 (1%)

NP

  1. 1 Estimated prevalence assuming that the prevalence of advanced ?brosis would be the same in the population of patients not reinvestigated. 2At least one factor of the metabolic syndrome without alcohol consumption at risk 3Alcohol consumption at risk self-reported or CDT >1.6% without metabolic factor 4Possibility of several confirmations for the same subject NP = not performed