Skip to main content

Table 1 The crypt/villi ratio in the rat distal small intestine.

From: Role of myosin light chain kinase in intestinal epithelial barrier defects in a rat model of bowel obstruction

Group Name

villous height (μm)

crypt depth (μm)

crypt/villi ratio

sham+v

252 ± 11

166 ± 11

0.667 ± 0.036

IO+v

237 ± 13

224 ± 15*

0.970 ± 0.061*

sham+ML-7

251 ± 23

154 ± 8

0.637 ± 0.059

IO+ML-7

283 ± 14

175 ± 13#

0.630 ± 0.025#

  1. Note. Distal small intestinal tissues from sham and IO rats treated with vehicle (labeled 'sham+v' and 'IO+v') or a MLCK inhibitor, ML-7 (labeled 'sham+ML-7' and 'IO+ML-7') were processed for histological examination. n = 6-7 rats per group. Values were expressed as mean ± SEM. *p < 0.05 vs. respective sham groups. #p < 0.05 vs. IO+v rats.