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Figure 1 | BMC Gastroenterology

Figure 1

From: Development of an invasively monitored porcine model of acetaminophen-induced acute liver failure

Figure 1

Acetaminophen concentrations (A) and Methaemoglobin levels (B) in pigs following acetaminophen administration. Panel A. Acetaminophen levels for individual pigs are noted, with the corresponding methaemoglobin levels illustrated in panel B. Acetaminophen levels of between 200 300 mg/l were aimed for although even with frequent measurements and reductions in the infusion rate there were rises often to 400 mg/l. Prolonged elevation of levels above 300 mg/l did lead to a rise in methaemoglobin. For pig 7 facilities to measure acetaminophen levels were unavailable and this led to a marked rise in methaemoglobin levels.

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