Tissue Compartment | Cell type | AT1R | AT2R | |
---|---|---|---|---|
Mucosa | Epithelium | Most epithelial cells | + mainly in basal parts | + mainly in basal parts |
Small epithelial cells in the base of glands | +++ in some endocrine like cells in antrum | n.o. | ||
Lamina propria | Vasculature | + in endothelium | + in endothelium | |
Nerve structures | n.o. | n.o. | ||
Mesenchymal cells |
++ in some cells; ++ in leucocytes in H. pylori-infected |
+ in some cells; ++ in leucocytes in H. pylori-infected | ||
Muscularis mucosae | Smooth muscle cells | ++ | + | |
Submucosa | Vasculature |
+ in endothelium; ++ in VSMCs |
+ in endothelium; n.o. in VSMCs | |
Nerve structures | n.o. | n.o. | ||
Mesenchymal cells |
++ in some cells; ++ in leucocytes in H. pylori-infected |
+ in some cells; ++ in leucocytes in H. pylori-infected | ||
Muscularis propria | Smooth muscle cells | ++ | + | |
Vasculature |
+ in endothelium; ++ in VSMCs |
+ in endothelium; n.o. in VSMCs | ||
Nerve structures | n.o. | n.o. | ||
Serosa | Vasculature |
n.o. in endothelium; ++ in VSMCs | n.o. |