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Table 1 Localization of AT1R and AT2R protein in the gastric wall of the Mongolian gerbil

From: Angiotensin II receptor expression and relation to Helicobacter pylori-infection in the stomach of the Mongolian gerbil

Tissue Compartment

 

Cell type

AT1R

AT2R

Mucosa

Epithelium

Most epithelial cells

+ mainly in basal parts

+ mainly in basal parts

  

Small epithelial cells in the base of glands

+++ in some endocrine like cells in antrum

n.o.

 

Lamina propria

Vasculature

+ in endothelium

+ in endothelium

  

Nerve structures

n.o.

n.o.

  

Mesenchymal cells

++ in some cells;

++ in leucocytes in H. pylori-infected

+ in some cells;

++ in leucocytes in H. pylori-infected

 

Muscularis mucosae

Smooth muscle cells

++

+

Submucosa

 

Vasculature

+ in endothelium;

++ in VSMCs

+ in endothelium;

n.o. in VSMCs

  

Nerve structures

n.o.

n.o.

  

Mesenchymal cells

++ in some cells;

++ in leucocytes in H. pylori-infected

+ in some cells;

++ in leucocytes in H. pylori-infected

Muscularis propria

 

Smooth muscle cells

++

+

  

Vasculature

+ in endothelium;

++ in VSMCs

+ in endothelium;

n.o. in VSMCs

  

Nerve structures

n.o.

n.o.

Serosa

 

Vasculature

n.o. in endothelium;

++ in VSMCs

n.o.

  1. n.o: not observed (or unspecific) immunoreactivity
  2. +: weak immunoreactivity but with distinct location
  3. ++: easily recognised immunoreactivity
  4. +++: strong immunoreactivity
  5. VSMCs: vascular smooth muscle cells