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Table 1 Localization of AT1R and AT2R protein in the gastric wall of the Mongolian gerbil

From: Angiotensin II receptor expression and relation to Helicobacter pylori-infection in the stomach of the Mongolian gerbil

Tissue Compartment   Cell type AT1R AT2R
Mucosa Epithelium Most epithelial cells + mainly in basal parts + mainly in basal parts
   Small epithelial cells in the base of glands +++ in some endocrine like cells in antrum n.o.
  Lamina propria Vasculature + in endothelium + in endothelium
   Nerve structures n.o. n.o.
   Mesenchymal cells ++ in some cells;
++ in leucocytes in H. pylori-infected 		+ in some cells;
++ in leucocytes in H. pylori-infected
  Muscularis mucosae Smooth muscle cells ++ +
Submucosa   Vasculature + in endothelium;
++ in VSMCs 		+ in endothelium;
n.o. in VSMCs
   Nerve structures n.o. n.o.
   Mesenchymal cells ++ in some cells;
++ in leucocytes in H. pylori-infected 		+ in some cells;
++ in leucocytes in H. pylori-infected
Muscularis propria   Smooth muscle cells ++ +
   Vasculature + in endothelium;
++ in VSMCs 		+ in endothelium;
n.o. in VSMCs
   Nerve structures n.o. n.o.
Serosa   Vasculature n.o. in endothelium;
++ in VSMCs 		n.o.
  1. n.o: not observed (or unspecific) immunoreactivity
  2. +: weak immunoreactivity but with distinct location
  3. ++: easily recognised immunoreactivity
  4. +++: strong immunoreactivity
  5. VSMCs: vascular smooth muscle cells
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BMC Gastroenterology

ISSN: 1471-230X

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