Tissue Compartment | Â | Cell type | AT1R | AT2R |
---|---|---|---|---|
Mucosa | Epithelium | Most epithelial cells | + mainly in basal parts | + mainly in basal parts |
 |  | Small epithelial cells in the base of glands | +++ in some endocrine like cells in antrum | n.o. |
 | Lamina propria | Vasculature | + in endothelium | + in endothelium |
 |  | Nerve structures | n.o. | n.o. |
 |  | Mesenchymal cells | ++ in some cells; ++ in leucocytes in H. pylori-infected | + in some cells; ++ in leucocytes in H. pylori-infected |
 | Muscularis mucosae | Smooth muscle cells | ++ | + |
Submucosa | Â | Vasculature | + in endothelium; ++ in VSMCs | + in endothelium; n.o. in VSMCs |
 |  | Nerve structures | n.o. | n.o. |
 |  | Mesenchymal cells | ++ in some cells; ++ in leucocytes in H. pylori-infected | + in some cells; ++ in leucocytes in H. pylori-infected |
Muscularis propria | Â | Smooth muscle cells | ++ | + |
 |  | Vasculature | + in endothelium; ++ in VSMCs | + in endothelium; n.o. in VSMCs |
 |  | Nerve structures | n.o. | n.o. |
Serosa | Â | Vasculature | n.o. in endothelium; ++ in VSMCs | n.o. |