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Figure 3 | BMC Gastroenterology

Figure 3

From: Prevalence of genetic polymorphisms in the promoter region of the alpha-1 antitrypsin (SERPINA1) gene in chronic liver disease: a case control study

Figure 3

Linkage disequilibrium (LD) plot across the SERPINA1 gene. Patients. Controls. The box at the top indicates the SERPINA1 gene with the 3 investigated SNP's (1 = p.E342K, 2 = p.E264V and 3 = c.-1973T >C). The LD plot is based on the measurement of R2 (values × 0.01). Each diamond indicates the pair wise magnitude of LD. (LD: linkage disequilibrium is the non-random association of alleles at two or more loci. LD describes a situation in which some combinations of alleles or genetic markers occur more or less frequently in a population than would be expected from a random formation of haplotypes from alleles based on their frequencies.)

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