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Table 2 Frequencies of cells with loss, normal status and gain in copy numbers of the target in chagasic megaesophagus and normal mucosa groups.

From: Chromosomal imbalances are uncommon in chagasic megaesophagus

 

<2 copies per cell

2 copies per cell

>2 copies per cell

Target

CM

NM

χ2test

CM

NM

CM

NM

FHIT

       

N

20

2

P = 10.672ns

2478

144

6

3

%

0.79

1.34

 

98.96

96.64

0.24

2.04

PIK3CA

       

N

898

57

P = 0.000*

1530

139

35

4

%

36.39

28.50

 

61.99

69.50

1.42

2.00

TP63

       

N

885

58

P = 2.579ns

2878

136

37

6

%

23.29

29.00

 

75.74

68.00

0.97

3.00

EGFR

       

N

298

12

P = 1.067ns

3433

187

171

1

%

7.59

6.00

 

88.03

93.50

4.38

0.50

FGFR1

       

N

928

68

P = 4.172ns

2833

121

46

1

%

24.38

34.00

 

74.41

60.50

1.21

0.50

MYC

       

N

918

62

P = 4.812ns

2849

135

33

2

%

24.00

31

 

75.00

67.50

0.01

1.00

CDKN2A

       

N

183

6

P = 17.702 ns

3649

194

68

0

%

4.69

3.00

 

93.56

97.00

1.74

0.00

YES1

       

N

1381

62

P = 2.171ns

2407

136

12

2

%

36.34

31.00

 

63.34

68.00

0.32

1.00

NCOA3

       

N

45

8

P = 3.627ns

2366

130

8

0

%

1.86

5.80

 

97.81

94.20

0.33

0.00

CEN3

       

N

683

54

P = 0.470ns

2510

145

7

1

%

21.0

27.0

 

78.44

72.5

0.56

0.50

CEP7

       

N

1637

56

P = 0.00+*

1509

1143

54

1

%

51.16

28.0

 

47.16

71.50

1.68

0.50

CEP9

       

N

1400

46

P = 0.00+*

1468

154

332

0

%

43.75

23.0

 

45.87

77.0

10.38

0.00

  1. CM, chagasic megaesophagus; NM, normal mucosa; SD, standard-deviation; Statistical Analysis: t-Student; *, P < 0.05; ns, P > 0.05; a, b, P = 0.008.