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Table 5 Risk score assessment according to the original and total tumor volume (TTV)-based CLIP scoring system

From: Prognostic prediction across a gradient of total tumor volume in patients with hepatocellular carcinoma undergoing locoregional therapy

Parameters Original CLIP TTV-based CLIP
Tumor morphology   
   Single and <50% liver span 0 -
   Multiple and <50% liver span 1 -
   ≥ 50% liver span 2 -
Total tumor volume   
   <50 cm3 - 0
   50-200 cm3 - 1
   200-500 cm3 - 2
   >500 cm3 - 3
Serum AFP level (ng/mL)   
   <400 0 0
   ≥ 400 1 1
Macroscopic vascular invasion   
   No 0 0
   Yes 1 1
CTP class   
   A 0 0
   B 1 1
   C 2 2
  1. The score range is 0-6 for the original CLIP and 0-7 for TTV-based CLIP scoring system.