TY - JOUR AU - Ritchie, Shawn A. AU - Heath, Doug AU - Yamazaki, Yasuyo AU - Grimmalt, Bryan AU - Kavianpour, Amir AU - Krenitsky, Kevin AU - Elshoni, Hoda AU - Takemasa, Ichiro AU - Miyake, Masakazu AU - Sekimoto, Mitsugu AU - Monden, Morito AU - Tomonaga, Takeshi AU - Matsubara, Hisahiro AU - Sogawa, Kazuyuki AU - Matsushita, Kazuyuki AU - Nomura, Fumio AU - Goodenowe, Dayan B. PY - 2010 DA - 2010/11/29 TI - Reduction of novel circulating long-chain fatty acids in colorectal cancer patients is independent of tumor burden and correlates with age JO - BMC Gastroenterology SP - 140 VL - 10 IS - 1 AB - Serum levels of novel hydroxy polyunsaturated ultra long-chain fatty acids (hPULCFAs) have been previously shown to be reduced in pre-treatment CRC patients compared to disease-free subjects, independent of disease stage. However, whether reduced levels of hPULCFAs result from the presence of cancer is currently unknown, as is the distribution of hPULCFAs in the general population. The following studies were carried out to assess whether conventional therapy would result in restoration of systemic hPULCFAs in CRC patients, and to investigate the relationship between hPULCFA levels and age. SN - 1471-230X UR - https://doi.org/10.1186/1471-230X-10-140 DO - 10.1186/1471-230X-10-140 ID - Ritchie2010 ER -