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Table 4 Multivariate analysis of 145 patients with gastric cancer for determining the significant prognostic factors

From: The gene-reduction effect of chromosomal losses detected in gastric cancers

Category Hazard ratio 95% CI Pvalue
Model 1 (stage II and III); Genotype variables    
   High- vs. low-risk genotype 22.077 6.57 - 74.18 < 0.0001
   Stage II vs. III 3.316 2.03 - 5.42 < 0.0001
   Vein invasion, no vs. yes 0.440 0.23 - 0848 0.014
   Age 1.001 0.98 - 1.03 0.957
   Sex 0.852 0.44 - 1.67 0.640
Model 2 (stage II and III); No genotype variables    
   Stage II vs. III 4.310 2.60 - 7.13 < 0.0001
   Growth pattern, 0.581 0.38 - 0.90 0.014
   Sex 2.079 1.02 - 4.24 0.044
   Age 0.989 0.97 - 1.02 0.370
Model 3 (stage II); Genotype variables    
   High- vs. low-risk genotype 15.42 1.71 - 139.5 0.015
Model 4 (stage II); No genotype variables    
   Tumor size 0.050 0.01 - 0.65 0.022
   Histological type 0.167 0.04 - 0.79 0.024
Model 5 (stage III); Genotype variables    
   High- vs. low-risk genotype 19.69 4.38 - 88.53 < 0.0001
   Tumor size 1.22 1.02 - 1.46 0.028
Model 6 (stage III); No genotype variables    
   Vein invasion, no vs. yes 0.30 0.13 - 0.70 0.006
  1. Hazard ratios were estimated in a multivariate analysis using a stepwise procedure. A variable in the model was entered when it was a significant independent factor (P < 0.05). Hazard ratios less than 1.00 represent a decreased risk of death, whereas hazard ratios greater than 1.00 represent an increased risk of death.
  2. CI, confidence interval.