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Table 2 The gene density, highly expressed genes, and LOH level on individual chromosomes estimated in stomach cancerous and noncancerous tissues

From: The gene-reduction effect of chromosomal losses detected in gastric cancers

  No. of genes per a 1-Mb segment* Top 100 highly expressed genes
(No. of transcripts per gene)*
Level of LOH (%)§
    Baseline
(n = 15)
Low
(n = 65)
High
(n = 50)
Cancer-associated chromosomes      
3 4.9 3 (76) 1 (7) 18 (28) 28 (56)
4 3.6 5 (53) 2 (13) 12 (18) 33 (66)
5 4.4 4 (44) 0 (0) 14 (22) 37 (74)
8 4.1 3 (32) 0 (0) 9 (14) 21 (42)
9 5.2 4 (60) 1 (7) 15 (23) 34 (68)
13 2.7 2 (121) 4 (27) 16 (25) 37 (74)
17 13.4 5 (42) 2 (13) 32 (49) 43 (86)
18 3.2 0 (0) 1 (7) 18 (28) 36 (72)
Mean values 4.8 3.3 (54)    
Other chromosomes      
1 7.7 8 (47)    
2 4.7 9 (132)    
6 5.8 7 (39)    
7 5.2 6 (45)    
10 5.0 2 (37)    
11 8.9 9 (85)    
12 7.3 10 (62)    
14 5.3 6 (43)    
15 5.3 2 (90)    
16 8.6 3 (34)    
19 19.8 8 (61)    
20 8.3 2 (76)    
21 5.1 1 (268)    
22 8.4 1 (55)    
Mean values 6.9 5.3 (69)    
  1. *The number of transcripts of 17,723 genes was analyzed using the previously published data [21].
  2. §The details are described in the material and methods section.