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Table 2 The frequency of under- and over-methylated cases as determined based on intermediate methylation levels common in the H. pylori-negative gastric mucosa (n = 100)

From: The overmethylated genes in Helicobacter pylori-infected gastric mucosa are demethylated in gastric cancers

Gene name Intermediate methylation density No. of under- methylated cases No. of intermediate methylation cases No. of over- methylated cases
CpG-island containing genes     
   CDH1 0 - 20% 0 79 21
   ARRDC4 0 - 20% 0 80 20
   PPARG 0 - 20% 0 60 40
   CDKN2A 0 - 20% 0 54 46
   TRAPPC2L 40 - 60% 13 81 6
   DUSP6 20 - 40% 26 62 12
   MLH1 20 - 40% 20 61 19
   RUNX3 30 - 50% 5 53 42
CpG-island lacking genes     
   PGA5 40 - 60% 10 78 12
   PGC 40 - 60% 29 67 4
   TFF1 20 - 40% 11 52 37
   TFF2 30 - 50% 36 60 4
   MSLN 60 - 80% 0 88 12
   KRT6A 60 - 80% 17 65 18