Figure 5

The frequency of overmethylated cases was compared between the gastric noncancerous and cancerous tissues. A total of 14 genes that were examined were grouped into three categories: (A) CpG-island-containing genes less than 3-kb close to the nearest retroelement; (B) CpG-island-containing genes more than 3-kb distant from the nearest retroelement; (C) The PGA5, PGC, TFF1, TFF2, MSLN and KRT6A genes. The asterisks and crosses indicate significant differences compared with the H. pylori negative and H. pylori positive gastric mucosa, respectively (P < 0.05). Student's t test was used.