Table 3 Genotypic distribution and allelic frequencies of IL-1 B polymorphisms in cases and controls.
Cases | ||||
|---|---|---|---|---|
511 T>C SNP | Controls n (%) | Chronic gastritis n (%) | Gastric ulcer n (%) | p-value |
Genotype | ||||
TT | 53 (52.0) | 31 (31.0) | 10 (35.7) | 0.015 θ |
TC | 39 (38.2) | 60 (60.0) | 13 (46.4) | |
CC | 10 (9.8) | 9 (9.0) | 5 (17.9) | |
Allele | ||||
T | 0.711 | 0.610 | 0.589 | 0.060 θ |
C | 0.289 | 0.390 | 0.411 | |
-31 C>T SNP | ||||
Genotype | ||||
CC | 52 (51.0) | 31 (31.0) | 10 (35.7) | 0.027 Ω |
CT | 42 (41.2) | 52 (52.0) | 16 (57.1) | |
TT | 8 (7.8) | 17 (17.0) | 2 (7.1) | |
Allele | ||||
C | 0.716 | 0.570 | 0.643 | 0.009 θ |
T | 0.284 | 0.430 | 0.357 | |