Figure 4
From: IQGAP1 and IQGAP2 are Reciprocally Altered in Hepatocellular Carcinoma
The Iqgap2 promoter is not hypermethylated in hepatocellular carcinoma. The degree of methylation for each CpG site was expressed as a percentage of methylated cytosines over the sum of total cytosines. The data are shown for 25 CpG sites and grouped by tissue type. Genomic DNA from the Kato III human gastric cancer cell line, which is known to have high methylation levels of the Iqgap2 gene promoter [23], was used as a positive control. The boxed area represents 50% of samples (from the 25th to the 75th percentile) and the band inside the box represents the median. Error bars (whiskers) indicate the 10th and 90th percentiles (shown only for plots with N = 9 or more). Symbols outside whiskers represent outliers.