Endoscopic treatments for Barrett's esophagus: a systematic review of safety and effectiveness compared to esophagectomy

Table 3 Numbers of included studies and patients

	Treatment	Number of studies	Comparative studies	Non-comparative studies	Number of patients
Endoscopic	PDT	37	5[13–16, 25]	32[22, 26–54]	1028
	APC	26	7[13–18, 55]	19[23, 56–73]	792
	Cryoablation	2	0	2[74, 75]	31
	Combined EMR & PDT	2	1[25]	1[76]	6
	Thermocoagulation	1	0	1[77]	13
	EMR	6	2[20, 25]	4[78–81]	38
	Laser ablation	7	0	7[24, 82–87]	91
	MPEC	6	2[17, 18]	4[88–90]	118
	RFA	16	2[19, 92]	14[93–105]	714
	Total*	95*	11*	86	2831
Surgical	Esophagectomy	8	3[21, 57, 79]	5[109–111]112	211
Total*		101*	12*	91	3042

Notes:(1) APC (argon plasma coagulation), EMR (endoscopic mucosal resection), MPEC (multipolar electrocoagulation), PDT (photodynamic therapy), RFA (radiofrequency ablation) (2) *9 comparative studies are reported in both intervention groups (e.g., APC and PDT), thus the number of separate comparative trials is less than the sum of entries in the column.

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