Figure 4
From: Lubiprostone ameliorates the cystic fibrosis mouse intestinal phenotype
Effect of lubiprostone on bacterial load in the small intestinal lumen of WT and CF mice. After an overnight fast, the contents of the small intestine were flushed with a mucolytic agent, and the flushed material was processed to measure copies of the bacterial 16 S rRNA gene by quantitative PCR (see Materials and Methods). Horizontal bars represent the group means. [5 WT control (Con), 12 WT + lubiprostone (Lubi), 6 CF control, 18 CF + lubiprostone; *: P = 0.008 CF control vs. WT control; +: P < 0.010 +Lubi vs. control of same genotype]