Figure 2
From: Ileal mucosal bile acid absorption is increased in Cftr knockout mice
Western Blot of Ileal Brush Border Proteins from Wild-Type, Heterozygous and Cystic Fibrosis Mice. An increase in IBAT protein concentration was observed in all examined brush border membrane vesicle preparations of the terminal ileum in knock-out mice. IBAT content approximately doubled in heterozygous knock-out mice and quadrupled in homozygous mutants compared to wild-type controls.