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  1. Research article

    Quality of life and impact of bile reflux after retro colic retro gastric gastrojejunostomy in Whipple surgery

    Delayed gastric emptying and bile reflux are common concerns in long-term survivors after Whipple surgery. The study was designed to assess modified retro colic retro gastric gastrojejunostomy in reducing macr...

    Rohan Chaminda Siriwardana, Rajapaksha Walimuni Mudiyanselage Anuradha Lokubandara, Shivanthi Janaki De Silva Hewavisenthi, Saumya Kumuduni Liyanage, Dona Subani Priyangika Jayatunge and Chandika Anuradha Habarakada Liyanage

    BMC Gastroenterology 2017 17:19

    Published on: 21 January 2017

  2. Research article

    Triple therapy versus sequential therapy for the first-line Helicobacter pylori eradication

    The eradication rate of Helicobacter pylori (H. pylori) with triple therapy which was considered as standard first-line treatment has decreased to 70–85%. The aim of this study is to compare 7-day triple therapy ...

    Ji Young Chang, Ki-Nam Shim, Chung Hyun Tae, Ko Eun Lee, Jihyun Lee, Kang Hoon Lee, Chang Mo Moon, Seong-Eun Kim, Hye-Kyung Jung and Sung-Ae Jung

    BMC Gastroenterology 2017 17:16

    Published on: 21 January 2017

  3. Research article

    Diagnosis of celiac disease and applicability of ESPGHAN guidelines in Mediterranean countries: a real life prospective study

    We assessed how the diagnosis of Celiac Disease (CD) is made and how the new ESPGHAN guidelines can be applied in children from countries with different resources.

    Andrea Smarrazzo, Zrinjka Misak, Stefano Costa, Dušanka Mičetić-Turk, Mona Abu-Zekry, Aydan Kansu, Abdelhak Abkari, Karim Bouziane-Nedjadi, Mongi Ben Hariz, Eleftheria Roma, Virtut Velmishi, Maria Legarda Tamara, Thomas Attard, Veselinka Djurisic, Luigi Greco and Giuseppe Magazzù

    BMC Gastroenterology 2017 17:17

    Published on: 21 January 2017

  4. Research article

    Health-related quality of Life in patients with chronic hepatitis C receiving Sofosbuvir-based treatment, with and without Interferon: a prospective observational study in Egypt

    The Egyptian government introduced the first directly acting antivirals (DAAs) into Egypt through the government funded National Treatment Program. As yet, there has been no investigation into the effects of t...

    Naglaa F. A. Youssef, Mohamed El Kassas, Amany Farag and Ashley Shepherd

    BMC Gastroenterology 2017 17:18

    Published on: 21 January 2017

  5. Research article

    Dietary treatment of Crohn’s disease: perceptions of families with children treated by exclusive enteral nutrition, a questionnaire survey

    Diet is strongly associated with the aetiology of Crohn’s Disease (CD) and exclusive enteral nutrition (EEN) is the primary induction treatment in paediatric CD. This study explored opinions around the use of ...

    Vaios Svolos, Konstantinos Gerasimidis, Elaine Buchanan, Lee Curtis, Vikki Garrick, Jacqueline Hay, Susan Laird, Joanna Munro, Daniel R. Gaya, Richard K. Russell and Richard Hansen

    BMC Gastroenterology 2017 17:14

    Published on: 19 January 2017

  6. Research article

    Telbivudine versus entecavir in patients with undetectable hepatitis B virus DNA: a randomized trial

    Telbivudine has been suggested to induce hepatitis B surface antigen (HBsAg) decline to the similar degree as pegylated interferon. We aimed to investigate whether telbivudine could further decrease HBsAg tite...

    Jihyun An, Young-Suk Lim, Gi-Ae Kim, Seong-bong Han, Wonhee Jeong, Danbi Lee, Ju Hyun Shim, Han Chu Lee and Yung Sang Lee

    BMC Gastroenterology 2017 17:15

    Published on: 19 January 2017

  7. Research article

    CTRC gene polymorphism (p.G60=; c.180 C > T) in acute pancreatitis

    The aim of the study was to determine the relationship between the presence of p.G60 = polymorphism (c.180C > T; rs497078) CTRC and the incidence together with the clinical course of acute pancreatitis (AP).

    Dorota Koziel, Stanislaw Gluszek, Artur Kowalik and Malgorzata Chlopek

    BMC Gastroenterology 2017 17:13

    Published on: 17 January 2017

  8. Research article

    Chronic constipation diagnosis and treatment evaluation: the “CHRO.CO.DI.T.E.” study

    According to Rome criteria, chronic constipation (CC) includes functional constipation (FC) and irritable bowel syndrome with constipation (IBS-C). Some patients do not meet these criteria (No Rome Constipatio...

    Massimo Bellini, Paolo Usai-Satta, Antonio Bove, Renato Bocchini, Francesca Galeazzi, Edda Battaglia, Pietro Alduini, Elisabetta Buscarini and Gabrio Bassotti

    BMC Gastroenterology 2017 17:11

    Published on: 14 January 2017

  9. Research article

    Prophylaxis of post-ERC infectious complications in patients with biliary obstruction by adding antimicrobial agents into ERC contrast media- a single center retrospective study

    Patients with biliary obstruction are at high risk to develop septic complications after endoscopic retrograde cholangiography (ERC). We evaluated the benefits of local application of antimicrobial agents into...

    Hella Wobser, Agnetha Gunesch and Frank Klebl

    BMC Gastroenterology 2017 17:10

    Published on: 13 January 2017

  10. Research article

    The cut-off value of tumor size and appropriate timing of follow-up for management of minimal EUS-suspected gastric gastrointestinal stromal tumors

    The detectable rate of minimal gastric GISTs has continuously increased. While the surveillance and management of GIST <2 cm have been deemed controversial or lack evidence-based approaches.  The aim of the cu...

    Zhidong Gao, Chao Wang, Qian Xue, Jingtong Wang, Zhanlong Shen, Kewei Jiang, Kai Shen, Bin Liang, Xiaodong Yang, Qiwei Xie, Shan Wang and Yingjiang Ye

    BMC Gastroenterology 2017 17:8

    Published on: 11 January 2017

  11. Research article

    A simple scoring model for advanced colorectal neoplasm in asymptomatic subjects aged 40–49 years

    Limited data are available for advanced colorectal neoplasm in asymptomatic individuals aged 40–49 years. We aimed to identify risk factors and develop a simple prediction model for advanced colorectal neoplas...

    Yoo Mi Park, Hee Sun Kim, Jae Jun Park, Su Jung Baik, Young Hoon Youn, Jie-Hyun Kim and Hyojin Park

    BMC Gastroenterology 2017 17:7

    Published on: 9 January 2017

  12. Research article

    High serum resistin associates with intrahepatic inflammation and necrosis: an index of disease severity for patients with chronic HBV infection

    Studies have revealed that resistin plays a role as an intrahepatic cytokine with proinflammatory activities. This study investigated the association between serum resistin and fibrosis severity and the possib...

    Zhongji Meng, Yonghong Zhang, Zhiqiang Wei, Ping Liu, Jian Kang, Yinhua Zhang, Deqiang Ma, Changzheng Ke, Yue Chen, Jie Luo and Zuojiong Gong

    BMC Gastroenterology 2017 17:6

    Published on: 7 January 2017

  13. Research article

    Comparison of risk adjustment methods in patients with liver disease using electronic medical record data

    Risk adjustment is essential for valid comparison of patients’ health outcomes or performances of health care providers. Several risk adjustment methods for liver diseases are commonly used but the optimal app...

    Yuan Xu, Ning Li, Mingshan Lu, Elijah Dixon, Robert P. Myers, Rachel J. Jolley and Hude Quan

    BMC Gastroenterology 2017 17:5

    Published on: 7 January 2017

  14. Research article

    A significant cancer burden and high mortality of intrahepatic cholangiocarcinoma in Thailand: a nationwide database study

    We aimed to examine the burden of intrahepatic cholangiocarcinoma (ICC) in Thailand and identify the prognostic factors for all-causes of death.

    Sombat Treeprasertsuk, Kittiyod Poovorawan, Ngamphol Soonthornworasiri, Roongruedee Chaiteerakij, Kessarin Thanapirom, Pisaln Mairiang, Kookwan Sawadpanich, Kanokwan Sonsiri, Varocha Mahachai and Kamthorn Phaosawasdi

    BMC Gastroenterology 2017 17:3

    Published on: 5 January 2017

  15. Research article

    Relationship of body weight with gastrointestinal motor and sensory function: studies in anorexia nervosa and obesity

    Whether gastrointestinal motor and sensory function is primary cause or secondary effect of abnormal body weight is uncertain. Moreover, studies relating continuous postprandial sensations of satiation to meas...

    Sena Bluemel, Dieter Menne, Gabriella Milos, Oliver Goetze, Michael Fried, Werner Schwizer, Mark Fox and Andreas Steingoetter

    BMC Gastroenterology 2017 17:4

    Published on: 5 January 2017

  16. Research article

    Clinical significance of UGT1A1 polymorphism and expression of ERCC1, BRCA1, TYMS, RRM1, TUBB3, STMN1 and TOP2A in gastric cancer

    Individualized therapeutic regimen is a recently intensively pursued approach for targeting diseases, in which the search for biomarkers was considered the first and most important. Thus, the goal of this stud...

    Yongkuan Cao, Guohu Zhang, Peihong Wang, Jun Zhou, Wei Gan, Yaning Song, Ling Huang, Ya Zhang, Guode Luo, Jiaqing Gong and Lin Zhang

    BMC Gastroenterology 2017 17:2

    Published on: 5 January 2017

  17. Research article

    Analyzing the influence of gastric intestinal metaplasia on gastric ulcer healing in Helicobacter pylori–infected patients without atrophic gastritis

    Gastric epithelial hyper-proliferation was reported in patients with Helicobacter pylori (H. pylori)–infected gastric mucosa with intestinal metaplasia (IM) changes. In patients with gastric ulcer (GU) and IM, th...

    Li-Wei Chen, Liang-Che Chang, Chung-Ching Hua, Bor-Jen Hsieh, Shuo-Wei Chen and Rong-Nan Chien

    BMC Gastroenterology 2017 17:1

    Published on: 3 January 2017

  18. Research article

    Smoking influences the need for surgery in patients with the inflammatory bowel diseases: a systematic review and meta-analysis incorporating disease duration

    Studies examining the association between smoking and the need for surgery in patients with Crohn’s disease and ulcerative colitis have reached inconsistent conclusions. These studies often do not differentiat...

    M. Ellen Kuenzig, Sang Min Lee, Bertus Eksteen, Cynthia H. Seow, Cheryl Barnabe, Remo Panaccione and Gilaad G. Kaplan

    BMC Gastroenterology 2016 16:143

    Published on: 21 December 2016

  19. Research article

    The prognostic influence of body mass index, resting energy expenditure and fasting blood glucose on postoperative patients with esophageal cancer

    Body mass index (BMI), resting energy expenditure (REE) and fasting blood glucose (FBG) are major preoperative assessments of patients’ nutrition and metabolic state. The relations and effects of these indices...

    Ning Wu, Yongjun Zhu, Dhruba Kadel, Liewen Pang, Gang Chen and Zhiming Chen

    BMC Gastroenterology 2016 16:142

    Published on: 21 December 2016

  20. Research article

    Analysis of association between circulating miR-122 and histopathological features of nonalcoholic fatty liver disease in patients free of hepatocellular carcinoma

    The association between circulating microRNA-122 (miR-122) and histopathological features of nonalcoholic fatty liver disease (NAFLD) remains unclear.

    Norio Akuta, Yusuke Kawamura, Fumitaka Suzuki, Satoshi Saitoh, Yasuji Arase, Shunichiro Fujiyama, Hitomi Sezaki, Tetsuya Hosaka, Masahiro Kobayashi, Yoshiyuki Suzuki, Mariko Kobayashi, Kenji Ikeda and Hiromitsu Kumada

    BMC Gastroenterology 2016 16:141

    Published on: 12 December 2016

  21. Research article

    Perceived stress as a risk factor for peptic ulcers: a register-based cohort study

    The association between stress and peptic ulcers has been questioned since the discovery of helicobacter pylori. This study examined whether high perceived everyday life stress was associated with an increased ri...

    Ulrik Deding, Linda Ejlskov, Mads Phillip Kofoed Grabas, Berit Jamie Nielsen, Christian Torp-Pedersen and Henrik Bøggild

    BMC Gastroenterology 2016 16:140

    Published on: 28 November 2016

  22. Research article

    Patients with longstanding ulcerative colitis in remission do not have more irritable bowel syndrome-like symptoms than controls

    Irritable bowel syndrome (IBS) is more common in patients with ulcerative colitis (UC) than expected. The prevalence of IBS in patients with UC with longstanding disease is not known. We investigated the preva...

    D. Lundgren, J. Rutegård, V. Eklöf, R. Palmqvist and P. Karling

    BMC Gastroenterology 2016 16:139

    Published on: 24 November 2016

  23. Case report

    Liver abscess and bacteremia caused by lactobacillus: role of probiotics? Case report and review of the literature

    Lactobacilli are non-spore forming, lactic acid producing, gram-positive rods. They are a part of the normal gastrointestinal and genitourinary microbiota and have rarely been reported to be the cause of infec...

    Muhammed Sherid, Salih Samo, Samian Sulaiman, Husein Husein, Humberto Sifuentes and Subbaramiah Sridhar

    BMC Gastroenterology 2016 16:138

    Published on: 18 November 2016

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