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  1. Research article

    Cholesterol esterification in plasma as a biomarker for liver function and prediction of mortality

    Advanced stages of liver cirrhosis lead to a dramatically increased mortality. For valid identification of these patients suitable biomarkers are essential. The most important biomarkers for liver function are...

    Thorsten Kaiser, Benedict Kinny-Köster, Michael Bartels, Thomas Berg, Markus Scholz, Cornelius Engelmann, Daniel Seehofer, Susen Becker, Uta Ceglarek and Joachim Thiery

    BMC Gastroenterology 2017 17:57

    Published on: 20 April 2017

  2. Research article

    Proteinuria and baseline renal function predict mortality and renal outcomes after sirolimus therapy in liver transplantation recipients

    Chronic kidney disease is a significant complication after liver transplantation (LT), but the role of pre-existing renal insufficiency and proteinuria remains unclear among LT recipients receiving sirolimus.

    Lung-Chih Li, Chien-Ning Hsu, Chih-Che Lin, Yu-Fan Cheng, Tsung-Hui Hu, Ding-Wei Chen, Chih-Hsiung Lee, Toshiaki Nakano and Chao-Long Chen

    BMC Gastroenterology 2017 17:58

    Published on: 20 April 2017

  3. Research article

    Findings in young adults at colonoscopy from a hospital service database audit

    Colorectal cancer (CRC) diagnosed at <50 years is predominantly located in the distal colon and rectum. Little is known about which lesion subtypes may serve as CRC precursors in young adults. The aim of this ...

    Stephanie Wong, Ilmars Lidums, Christophe Rosty, Andrew Ruszkiewicz, Susan Parry, Aung Ko Win, Yoko Tomita, Sina Vatandoust, Amanda Townsend, Dainik Patel, Jennifer E. Hardingham, David Roder, Eric Smith, Paul Drew, Julie Marker, Wendy Uylaki…

    BMC Gastroenterology 2017 17:56

    Published on: 19 April 2017

  4. Research article

    Vitamin D-related gene polymorphism predict treatment response to pegylated interferon-based therapy in Thai chronic hepatitis C patients

    Patients with chronic hepatitis C (HCV) infection have high prevalence of vitamin D deficiency. Genome-wide association study data has showed that several genetic variants within vitamin D cascade affect vitam...

    Kessarin Thanapirom, Sirinporn Suksawatamnuay, Wattana Sukeepaisarnjaroen, Pisit Tangkijvanich, Sombat Treeprasertsuk, Panarat Thaimai, Rujipat Wasitthankasem, Yong Poovorawan and Piyawat Komolmit

    BMC Gastroenterology 2017 17:54

    Published on: 17 April 2017

  5. Research article

    Lactobacillus casei DG and its postbiotic reduce the inflammatory mucosal response: an ex-vivo organ culture model of post-infectious irritable bowel syndrome

    The evidence on the role of gut microbiota in post-infectious irritable bowel syndrome (PI-IBS) is convincing. Lactobacillus spp. positively affect IBS symptoms, although the mechanisms through which probiotic...

    Debora Compare, Alba Rocco, Pietro Coccoli, Debora Angrisani, Costantino Sgamato, Barbara Iovine, Umberto Salvatore and Gerardo Nardone

    BMC Gastroenterology 2017 17:53

    Published on: 14 April 2017

  6. Research article

    Inflammatory Bowel Disease (IBD) pharmacotherapy and the risk of serious infection: a systematic review and network meta-analysis

    The magnitude of risk of serious infections due to available medical therapies of inflammatory bowel disease (IBD) remains controversial. We conducted a systematic review and network meta-analysis of the exist...

    Chelle L. Wheat, Cynthia W. Ko, Kindra Clark-Snustad, David Grembowski, Timothy A. Thornton and Beth Devine

    BMC Gastroenterology 2017 17:52

    Published on: 14 April 2017

  7. Research article

    The inverse effect of meal intake on controlled attenuation parameter and liver stiffness as assessed by transient elastography

    Controlled attenuation parameter (CAP) and liver stiffness (LS) measured by transient elastography (TE, Fibroscan®) have been used for steatosis and fibrosis assessment. We evaluated the effect of meal intake ...

    Kanittha Ratchatasettakul, Sasivimol Rattanasiri, Kwannapa Promson, Pranee Sringam and Abhasnee Sobhonslidsuk

    BMC Gastroenterology 2017 17:50

    Published on: 13 April 2017

  8. Research article

    The relationship of serum alanine aminotransferase normal-range levels to arterial stiffness and metabolic syndrome in non-drinkers and drinkers: a Chinese community-based analysis

    Few studies have investigated the relationship between carotid-femoral pulse wave velocity (cfPWV) and serum alanine aminotransferase (ALT) normal-range levels across the world. The current analysis was design...

    Shihui Fu, Ying Lin, Leiming Luo and Ping Ye

    BMC Gastroenterology 2017 17:49

    Published on: 11 April 2017

  9. Research article

    Costs and quality of life of small-incision open cholecystectomy and laparoscopic cholecystectomy - an expertise-based randomised controlled trial

    Health care providers need solid evidence based data on cost differences between alternative surgical procedures for common surgical disorders. We aimed to compare small-incision open cholecystectomy (SIOC) an...

    Mats H. Rosenmüller, Erik Nilsson, Fredrik Lindberg, Sten-Olof Åberg and Markku M. Haapamäki

    BMC Gastroenterology 2017 17:48

    Published on: 8 April 2017

  10. Research article

    Real life results in using 5-ASA for maintaining mild to moderate UC patients in Japan, a multi-center study, OPTIMUM Study

    Efficacy of maintenance therapy in ulcerative colitis (UC) in the remission stage has been reported to depend on release profile or dosing regimen of oral 5-aminosalicylic acid (5-ASA) products used. Aim of th...

    Masakazu Nagahori, Shuji Kochi, Hiroyuki Hanai, Takayuki Yamamoto, Shiro Nakamura, Soji Omuro, Mamoru Watanabe and Toshifumi Hibi

    BMC Gastroenterology 2017 17:47

    Published on: 4 April 2017

  11. Research article

    Comparison of five tumor regression grading systems for gastric adenocarcinoma after neoadjuvant chemotherapy: a retrospective study of 192 cases from National Cancer Center in China

    Neoadjuvant chemotherapy has been increasingly practiced on gastric cancer (GC), and histological evaluation to predict outcome is urgent in clinical practice. There are five classic tumor regression grading (...

    Yuelu Zhu, Yongkun Sun, Shangying Hu, Yong Jiang, Jiangying Yue, Xuemin Xue, Lin Yang and Liyan Xue

    BMC Gastroenterology 2017 17:41

    Published on: 14 March 2017

  12. Research article

    A preliminary investigation on single nucleotide polymorphism rs2287622 of bile salt export pump gene in patients with chronic hepatitis C virus infection in Hunan, China

    European researchers have underscored associations between single nucleotide polymorphism (SNP) rs2287622 of the hepatobiliary bile salt export pump (BSEP) gene and the risk of hepatitis C virus (HCV) infectio...

    Jian-Hua Lei, Xu Yang, Xin-Qiang Xiao, Zi Chen and Feng Peng

    BMC Gastroenterology 2017 17:42

    Published on: 14 March 2017

  13. Research article

    The utility of apoptosis inhibitor of macrophages as a possible diagnostic marker in patients with Crohn’s disease

    Apoptosis inhibitor of macrophages (AIM) was initially identified as an apoptosis inhibitor that supports the survival of macrophages against various apoptosis-inducing stimuli, and AIM produced by macrophages...

    Yohei Ono, Shuji Kanmura, Yuko Morinaga, Kohei Oda, Katsuto Kawabata, Shiho Arima, Fumisato Sasaki, Yuichirou Nasu, Shiroh Tanoue, Shinichi Hashimoto, Hiroki Taguchi, Hirofumi Uto, Hirohito Tsubouchi and Akio Ido

    BMC Gastroenterology 2017 17:40

    Published on: 11 March 2017

  14. Research article

    Comparison of the long-term efficacy between entecavir and tenofovir in treatment- naïve chronic hepatitis B patients

    There have been limited studies directly comparing the long-term efficacy between entecavir (ETV) and tenofovir disoproxil fumarate (TDF). This study was aimed to compare the long-term efficacy between them in...

    Ji Won Park, Kyeong Min Kwak, Sung Eun Kim, Myoung Kuk Jang, Ki Tae Suk, Dong Joon Kim, Sang Hoon Park, Myung Seok Lee, Hyoung Su Kim and Choong Kee Park

    BMC Gastroenterology 2017 17:39

    Published on: 9 March 2017

  15. Research article

    The H.O.U.S.E. classification: a novel endoscopic retrograde cholangiopancreatography (ERCP) complexity grading scale

    Endoscopic retrograde cholangiopancreatography (ERCP) is a technically challenging endoscopic procedure, harboring a wide range of complexities within every single investigation. Classifications of the complex...

    Greger Olsson, Urban Arnelo, Fredrik Swahn, Björn Törnqvist, Lars Lundell and Lars Enochsson

    BMC Gastroenterology 2017 17:38

    Published on: 9 March 2017

  16. Case report

    A case of type 1 multiple endocrine neoplasia with esophageal stricture successfully treated with endoscopic balloon dilation and local steroid injection combined with surgical resection of gastrinomas

    In type 1 multiple endocrine neoplasia (MEN1), esophageal diseases association with excessive gastrin secretion in Zollinger-Ellison syndrome (ZES) sometimes develop. Here, we reported a case of MEN1/ZES, who ...

    Hiroyuki Matsubayashi, Noboru Kawata, Naomi Kakushima, Masaki Tanaka, Kohei Takizawa, Yoshimi Kiyozumi, Yasue Horiuchi, Keiko Sasaki, Teiichi Sugiura, Katsuhiko Uesaka and Hiroyuki Ono

    BMC Gastroenterology 2017 17:37

    Published on: 7 March 2017

  17. Research article

    “Non alcoholic fatty liver disease and eNOS dysfunction in humans”

    NAFLD is associated to Insulin Resistance (IR). IR is responsible for Endothelial Dysfunction (ED) through the impairment of eNOS function. Although eNOS derangement has been demonstrated in experimental model...

    Marcello Persico, Mario Masarone, Antonio Damato, Mariateresa Ambrosio, Alessandro Federico, Valerio Rosato, Tommaso Bucci, Albino Carrizzo and Carmine Vecchione

    BMC Gastroenterology 2017 17:35

    Published on: 7 March 2017

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