Hepatobiliary and pancreatic disorders

Section edited by Emmanuel A Tsochatzis and Rakesh Tandon

This section concerns all clinical and basic science aspects of hepatobiliary and pancreatic disorders including but not limited to: prevention, diagnosis and management, as well as related molecular genetics and pathophysiology.

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  1. Research article

    Efficacy of chemotherapy in elderly patients with unresectable pancreatic cancer: a multicenter review of 895 patients

    The efficacy of chemotherapy for unresectable pancreatic cancer has improved. However, it is occasionally difficult to make treatment decisions for elderly patients. We reviewed the outcomes of elderly patient...

    Taira Kuroda, Teru Kumagi, Tomoyuki Yokota, Nobuaki Azemoto, Aki Hasebe, Hirotaka Seike, Mari Nishiyama, Nobu Inada, Naozumi Shibata, Hideki Miyata, Tomoe Kawamura, Yusuke Imai, Akiko Ueno-Toshimori, Yoshinori Tanaka, Takashi Terao, Yoshiki Imamura…

    BMC Gastroenterology 2017 17:66

    Published on: 22 May 2017

  2. Research article

    Accuracy of M2BPGi, compared with Fibro Scan®, in analysis of liver fibrosis in patients with hepatitis C

    Mac-2 Binding Protein Glycosylation isomer (M2BPGi) is a novel serological glyco-biomarker for staging liver fibrosis. Here, we aimed to evaluate the efficiency of serum M2BPGi in identifying liver fibrosis st...

    Hongqin Xu, Wenli Kong, Lei Liu, Xiumei Chi, Xiaomei Wang, Ruihong Wu, Xiuzhu Gao, Huan Wang, Limei Qu, Yue Qi, Yu Pan and Junqi Niu

    BMC Gastroenterology 2017 17:62

    Published on: 10 May 2017

  3. Research article

    Noninvasive assessment of liver steatosis in children: the clinical value of controlled attenuation parameter

    To assess the clinical validity of controlled attenuation parameter (CAP) in the diagnosis of hepatic steatosis in a series of overweight or obese children by using the imperfect gold standard methodology.

    Giovanna Ferraioli, Valeria Calcaterra, Raffaella Lissandrin, Marinella Guazzotti, Laura Maiocchi, Carmine Tinelli, Annalisa De Silvestri, Corrado Regalbuto, Gloria Pelizzo, Daniela Larizza and Carlo Filice

    BMC Gastroenterology 2017 17:61

    Published on: 4 May 2017

  4. Research article

    Cholesterol esterification in plasma as a biomarker for liver function and prediction of mortality

    Advanced stages of liver cirrhosis lead to a dramatically increased mortality. For valid identification of these patients suitable biomarkers are essential. The most important biomarkers for liver function are...

    Thorsten Kaiser, Benedict Kinny-Köster, Michael Bartels, Thomas Berg, Markus Scholz, Cornelius Engelmann, Daniel Seehofer, Susen Becker, Uta Ceglarek and Joachim Thiery

    BMC Gastroenterology 2017 17:57

    Published on: 20 April 2017

  5. Research article

    Proteinuria and baseline renal function predict mortality and renal outcomes after sirolimus therapy in liver transplantation recipients

    Chronic kidney disease is a significant complication after liver transplantation (LT), but the role of pre-existing renal insufficiency and proteinuria remains unclear among LT recipients receiving sirolimus.

    Lung-Chih Li, Chien-Ning Hsu, Chih-Che Lin, Yu-Fan Cheng, Tsung-Hui Hu, Ding-Wei Chen, Chih-Hsiung Lee, Toshiaki Nakano and Chao-Long Chen

    BMC Gastroenterology 2017 17:58

    Published on: 20 April 2017

  6. Research article

    Vitamin D-related gene polymorphism predict treatment response to pegylated interferon-based therapy in Thai chronic hepatitis C patients

    Patients with chronic hepatitis C (HCV) infection have high prevalence of vitamin D deficiency. Genome-wide association study data has showed that several genetic variants within vitamin D cascade affect vitam...

    Kessarin Thanapirom, Sirinporn Suksawatamnuay, Wattana Sukeepaisarnjaroen, Pisit Tangkijvanich, Sombat Treeprasertsuk, Panarat Thaimai, Rujipat Wasitthankasem, Yong Poovorawan and Piyawat Komolmit

    BMC Gastroenterology 2017 17:54

    Published on: 17 April 2017

  7. Research article

    The inverse effect of meal intake on controlled attenuation parameter and liver stiffness as assessed by transient elastography

    Controlled attenuation parameter (CAP) and liver stiffness (LS) measured by transient elastography (TE, Fibroscan®) have been used for steatosis and fibrosis assessment. We evaluated the effect of meal intake ...

    Kanittha Ratchatasettakul, Sasivimol Rattanasiri, Kwannapa Promson, Pranee Sringam and Abhasnee Sobhonslidsuk

    BMC Gastroenterology 2017 17:50

    Published on: 13 April 2017

  8. Research article

    The relationship of serum alanine aminotransferase normal-range levels to arterial stiffness and metabolic syndrome in non-drinkers and drinkers: a Chinese community-based analysis

    Few studies have investigated the relationship between carotid-femoral pulse wave velocity (cfPWV) and serum alanine aminotransferase (ALT) normal-range levels across the world. The current analysis was design...

    Shihui Fu, Ying Lin, Leiming Luo and Ping Ye

    BMC Gastroenterology 2017 17:49

    Published on: 11 April 2017

  9. Research article

    Costs and quality of life of small-incision open cholecystectomy and laparoscopic cholecystectomy - an expertise-based randomised controlled trial

    Health care providers need solid evidence based data on cost differences between alternative surgical procedures for common surgical disorders. We aimed to compare small-incision open cholecystectomy (SIOC) an...

    Mats H. Rosenmüller, Erik Nilsson, Fredrik Lindberg, Sten-Olof Åberg and Markku M. Haapamäki

    BMC Gastroenterology 2017 17:48

    Published on: 8 April 2017

  10. Research article

    A preliminary investigation on single nucleotide polymorphism rs2287622 of bile salt export pump gene in patients with chronic hepatitis C virus infection in Hunan, China

    European researchers have underscored associations between single nucleotide polymorphism (SNP) rs2287622 of the hepatobiliary bile salt export pump (BSEP) gene and the risk of hepatitis C virus (HCV) infectio...

    Jian-Hua Lei, Xu Yang, Xin-Qiang Xiao, Zi Chen and Feng Peng

    BMC Gastroenterology 2017 17:42

    Published on: 14 March 2017

  11. Research article

    Comparison of the long-term efficacy between entecavir and tenofovir in treatment- naïve chronic hepatitis B patients

    There have been limited studies directly comparing the long-term efficacy between entecavir (ETV) and tenofovir disoproxil fumarate (TDF). This study was aimed to compare the long-term efficacy between them in...

    Ji Won Park, Kyeong Min Kwak, Sung Eun Kim, Myoung Kuk Jang, Ki Tae Suk, Dong Joon Kim, Sang Hoon Park, Myung Seok Lee, Hyoung Su Kim and Choong Kee Park

    BMC Gastroenterology 2017 17:39

    Published on: 9 March 2017

  12. Research article

    The H.O.U.S.E. classification: a novel endoscopic retrograde cholangiopancreatography (ERCP) complexity grading scale

    Endoscopic retrograde cholangiopancreatography (ERCP) is a technically challenging endoscopic procedure, harboring a wide range of complexities within every single investigation. Classifications of the complex...

    Greger Olsson, Urban Arnelo, Fredrik Swahn, Björn Törnqvist, Lars Lundell and Lars Enochsson

    BMC Gastroenterology 2017 17:38

    Published on: 9 March 2017

  13. Research article

    “Non alcoholic fatty liver disease and eNOS dysfunction in humans”

    NAFLD is associated to Insulin Resistance (IR). IR is responsible for Endothelial Dysfunction (ED) through the impairment of eNOS function. Although eNOS derangement has been demonstrated in experimental model...

    Marcello Persico, Mario Masarone, Antonio Damato, Mariateresa Ambrosio, Alessandro Federico, Valerio Rosato, Tommaso Bucci, Albino Carrizzo and Carmine Vecchione

    BMC Gastroenterology 2017 17:35

    Published on: 7 March 2017

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